. . . . "Effect of Creatine Applied as Food Supplement on Human Metabolism"@en . "Effect of Creatine Applied as Food Supplement on Human Metabolism"@en . . "P\u0159istoupilov\u00E1, Kamila" . . . . . "RIV/00216208:11510/10:10071295" . . "[78DC68F9AEE1]" . . . "Petr, Miroslav" . . "4"^^ . "thiodiglycolic acid (TDGA); homocysteine; human metabolism; vitamin B12; folate; supplementation; creatine"@en . "Effect of Creatine Applied as Food Supplement on Human Metabolism" . "Creatine (CR), is recommended for application as food supplement. It is supposed that human organism uses it for formation of CR phosphate as source of energy. In our short-term experiments we have observed changes in the metabolism of two-carbon (2C) units and of thiolic substances 4 to 6 hours after CR supplementation. The level of thiodiglycolic acid (TDGA) in urine increased rapidly and then decreased again to the original level. The level of TDGA in urine is a marker of disturbance in metabolic pathways of 2C units and of thiolic compounds. Our long-term CR supplementation, revealed that the biochemical pathways, affected by CR application included intrinsic participation of vitamin B12 and folates. The levels of those two vitamins changed in a mutually reverse way. The men under study can be divided into 4 different groups according to changes of CR levels found in urine, and of levels of folates and vitamin B12, determined in blood before and after CR administration." . "11510" . . "Z(MSM0021620864)" . "Creatine (CR), is recommended for application as food supplement. It is supposed that human organism uses it for formation of CR phosphate as source of energy. In our short-term experiments we have observed changes in the metabolism of two-carbon (2C) units and of thiolic substances 4 to 6 hours after CR supplementation. The level of thiodiglycolic acid (TDGA) in urine increased rapidly and then decreased again to the original level. The level of TDGA in urine is a marker of disturbance in metabolic pathways of 2C units and of thiolic compounds. Our long-term CR supplementation, revealed that the biochemical pathways, affected by CR application included intrinsic participation of vitamin B12 and folates. The levels of those two vitamins changed in a mutually reverse way. The men under study can be divided into 4 different groups according to changes of CR levels found in urine, and of levels of folates and vitamin B12, determined in blood before and after CR administration."@en . "255921" . . "Kohl\u00EDkov\u00E1, Eva" . "2"^^ . . . . "RIV/00216208:11510/10:10071295!RIV11-MSM-11510___" . . . "Effect of Creatine Applied as Food Supplement on Human Metabolism" . "Navr\u00E1til, Tom\u00E1\u0161" .