"Szanyi, Jana" . . . "Langrov\u00E1, Jana" . "10.1007/s10633-014-9429-y" . "Background In adults, motion-onset visual evoked potentials (M-VEPs) with a dominant N2 peak represent a useful diagnostic tool. However, it is difficult to use this type of VEP in children because of the long maturation (up to 18 years) of M-VEPs, which is characterised by a gradual decrease in N2 peak latency and shape development. Moreover, in some children, M-VEPs are difficult to identify with standard stimuli. Methods We tested features of M-VEPs in 30 children (7-12 years) with the following set of standard stimuli used in our lab for examining adults (https://web.lfhk.cuni.cz/elf): low-contrast translation motion (TM) and expansion/contraction motion (ExCoM) in full field and in periphery (with central 20 degrees masked). In 16 children, a high-contrast TM was also tested. Results With standard (low-contrast) stimuli, a common M-VEP to TM and to ExCoM was detected in 77 and 83 % of children, respectively. The M-VEPs to ExCoM in the periphery were detected in only 43 % of children. An abnormal dominant P1 peak was found in 9 % of VEPs to TM, 12 % of VEPs to full-field ExCoM and 14 % of VEPs to peripheral ExCoM. The M-VEPs to all low-contrast stimuli displayed large inter-individual latency variability (N2 peak latency differed for more than 100 ms). High contrast (more suitable for the non-mature magnocellular pathway) shortened M-VEP latencies and improved amplitudes. Conclusions Our findings show that the maturation of motion perception in children is inter-individually variable, which limits the diagnostic use of M-VEPs." . "9"^^ . . "Difficulties of motion-onset VEP interpretation in school-age children" . . . . . . . "11150" . "RIV/00216208:11150/14:10281337" . "NL - Nizozemsko" . "7"^^ . "000333129400005" . . "11502" . "http://dx.doi.org/10.1007/s10633-014-9429-y" . "7"^^ . "I, P(GA309/09/0869)" . . . "Difficulties of motion-onset VEP interpretation in school-age children"@en . "V\u00EDt, Franti\u0161ek" . "Kreml\u00E1\u010Dek, Jan" . . "Difficulties of motion-onset VEP interpretation in school-age children"@en . "128" . . . . "0012-4486" . "Difficulties of motion-onset VEP interpretation in school-age children" . "RIV/00216208:11150/14:10281337!RIV15-MSM-11150___" . . "Kubov\u00E1, Zuzana" . . . . . . "Chutn\u00E1, Marie" . "Children; M-VEPs; VEPs; Motion-onset visual evoked potentials"@en . "Kuba, Miroslav" . "[472B006E9699]" . "Documenta Ophthalmologica" . . "2" . "Background In adults, motion-onset visual evoked potentials (M-VEPs) with a dominant N2 peak represent a useful diagnostic tool. However, it is difficult to use this type of VEP in children because of the long maturation (up to 18 years) of M-VEPs, which is characterised by a gradual decrease in N2 peak latency and shape development. Moreover, in some children, M-VEPs are difficult to identify with standard stimuli. Methods We tested features of M-VEPs in 30 children (7-12 years) with the following set of standard stimuli used in our lab for examining adults (https://web.lfhk.cuni.cz/elf): low-contrast translation motion (TM) and expansion/contraction motion (ExCoM) in full field and in periphery (with central 20 degrees masked). In 16 children, a high-contrast TM was also tested. Results With standard (low-contrast) stimuli, a common M-VEP to TM and to ExCoM was detected in 77 and 83 % of children, respectively. The M-VEPs to ExCoM in the periphery were detected in only 43 % of children. An abnormal dominant P1 peak was found in 9 % of VEPs to TM, 12 % of VEPs to full-field ExCoM and 14 % of VEPs to peripheral ExCoM. The M-VEPs to all low-contrast stimuli displayed large inter-individual latency variability (N2 peak latency differed for more than 100 ms). High contrast (more suitable for the non-mature magnocellular pathway) shortened M-VEP latencies and improved amplitudes. Conclusions Our findings show that the maturation of motion perception in children is inter-individually variable, which limits the diagnostic use of M-VEPs."@en .