"RIV/00216208:11150/09:00208517" . . . "Holick\u00E1, Monika" . "Francisella tularensis; macrophage; interferon-gamma; lipopolysaccharide"@en . "5"^^ . "Troj\u00E1\u010Dkov\u00E1-Kudlov\u00E1, Manuela" . . . . "Krejsek, Jan" . "The effect of interferon-gamma and lipopolysaccharide on the growth of Francisella tularensis LVS in murine macrophage-like cell line J774"@en . "CZ - \u010Cesk\u00E1 republika" . "The effect of interferon-gamma and lipopolysaccharide on the growth of Francisella tularensis LVS in murine macrophage-like cell line J774"@en . . . . "52" . "The effect of interferon-gamma and lipopolysaccharide on the growth of Francisella tularensis LVS in murine macrophage-like cell line J774" . "The effect of interferon-gamma and lipopolysaccharide on the growth of Francisella tularensis LVS in murine macrophage-like cell line J774" . "3" . "P(LN00A033)" . "Novosad, Jakub" . . . "11150" . "Background: Francisella tularensis, a causative agent of human tularemia, displaying the ability to proliferate inside the human cells. Aims: To evaluate the growth potential of F. tularensis LVS strain in macrophage-like cell line J774 modulated by recombinant interferon gama and E. coli derived lipopolysaccharide. Results: Stimulation of J774 cells either by interferon-gama or lipopolysaccharide alone, or especially in combination before infection F. tularensis, revealed protective effects. Higher concentrations of stimulating agents were needed to inhibit ongoing F. tularensis infection. Conclusions: Stimulation of J774 cell line by combination of interferon-gama with lipopolysaccharide inhibits the intracellular growth of F. tularensis." . . "6"^^ . "Acta Medica (Hradec Kr\u00E1lov\u00E9)" . . "1211-4286" . . . "312141" . . "RIV/00216208:11150/09:00208517!RIV10-MSM-11150___" . . "Background: Francisella tularensis, a causative agent of human tularemia, displaying the ability to proliferate inside the human cells. Aims: To evaluate the growth potential of F. tularensis LVS strain in macrophage-like cell line J774 modulated by recombinant interferon gama and E. coli derived lipopolysaccharide. Results: Stimulation of J774 cells either by interferon-gama or lipopolysaccharide alone, or especially in combination before infection F. tularensis, revealed protective effects. Higher concentrations of stimulating agents were needed to inhibit ongoing F. tularensis infection. Conclusions: Stimulation of J774 cell line by combination of interferon-gama with lipopolysaccharide inhibits the intracellular growth of F. tularensis."@en . "[2221D166F946]" . . "3"^^ . "Loudov\u00E1, Martina" . .