"In vitro and in vivo examination of cardiac troponins as biochemical markers of drug-induced cardiotoxicity" . "drug-induced cardiotoxicity; anthracycline cardiotoxicity; daunorubicin; cardiac troponin I (cTnI); cardiac troponin T (cTnT)"@en . . . "In vitro and in vivo examination of cardiac troponins as biochemical markers of drug-induced cardiotoxicity"@en . . . . . . "11150" . . . . . . . . "Adamcov\u00E1, Michaela" . . "218;228" . "Popelov\u00E1, Olga" . "1-3" . "Srde\u010Dn\u00ED troponiny jako markery kardiotoxicity v pokusech in vitro a in vivo"@cs . "In vitro and in vivo examination of cardiac troponins as biochemical markers of drug-induced cardiotoxicity"@en . "Studie se zab\u00FDv\u00E1 kinetikou uvoln\u011Bn\u00ED cTnT a cTnI na modelu NVCM in vitro a z\u00E1rove\u0148 na modelu antracykliny-indukovan\u00E9 kardiomyopatie in vivo. P\u0159i d\u00E1vce 3 uM daunorubicinu se AUC pro cTnT zv\u00FD\u0161ila 2,4x a pro cTnI 5,3x ve srovn\u00E1n\u00ED s LDH."@cs . . "In this study we examined the release kinetics of cTnT and cTnI using an in vitro model of NVCM and compared it with data from a model of anthracycline-induced cardiomyopathy in vivo. With 3 uM daunorubicin, the relative increase of AUC of cTnT and cTnI was 2.4 and 5.3-fold higher than the increase of LDH activity, respectively." . . "Ger\u0161l, Vladim\u00EDr" . "[85167E0B4C09]" . "\u0160t\u011Brba, Martin" . "11"^^ . . . "In vitro and in vivo examination of cardiac troponins as biochemical markers of drug-induced cardiotoxicity" . "Srde\u010Dn\u00ED troponiny jako markery kardiotoxicity v pokusech in vitro a in vivo"@cs . . "RIV/00216208:11150/07:00003798" . "237" . "425847" . "Toxicology" . "5"^^ . "0300-483X" . "P(GP305/05/P156), V, Z(MSM0021620820)" . . "Pot\u00E1\u010Dov\u00E1, Anna" . "NL - Nizozemsko" . . "RIV/00216208:11150/07:00003798!RIV08-MSM-11150___" . . "9"^^ . . "In this study we examined the release kinetics of cTnT and cTnI using an in vitro model of NVCM and compared it with data from a model of anthracycline-induced cardiomyopathy in vivo. With 3 uM daunorubicin, the relative increase of AUC of cTnT and cTnI was 2.4 and 5.3-fold higher than the increase of LDH activity, respectively."@en .