"Z(MSM0021620816), Z(MZ0FNHK2005)" . . . . "Prolactin as a factor for increased platelet aggregation"@en . "SE - \u0160v\u00E9dsk\u00E9 kr\u00E1lovstv\u00ED" . . . "6"^^ . "Hos\u00E1k, Ladislav" . "445302" . . "Kalnick\u00E1, Dita" . . . . . . . . "RIV/00216208:11150/07:00003697!RIV08-MSM-11150___" . "0172-780X" . "Administration of antipsychotics appears to be related to increased risk of venous thromboembolism and cerebrovascular side effects. The biological mechanism responsible for this possible adverse drug reaction is unknown, but there is a growing number of elucidating hypotheses. Treatment with antipsychotics is a asssociated with elevation of prolactin level. Prolactin has recently been recognized as potent platelet aggregation co-activator, and have therefore been postulated as an addditional risk factor for both arterial and venous thrombosis. We briefly review the arguments for the role of hyperprolactinemia in pathogenesis of platelet aggregation."@en . . "Prolaktin jako faktor zv\u00FD\u0161en\u00E9ho sr\u00E1\u017Een\u00ED krevn\u00EDch desti\u010Dek"@cs . . . . . . . . "4" . "Prolactin as a factor for increased platelet aggregation"@en . "11150" . . "prolactin; hyperprolactinemia; platelet activation; platelet aggregation; antipsychotics; venous thrombosis; cerebrovascular complications"@en . "Prolactin as a factor for increased platelet aggregation" . "5"^^ . "RIV/00216208:11150/07:00003697" . "Prolaktin jako faktor zv\u00FD\u0161en\u00E9ho sr\u00E1\u017Een\u00ED krevn\u00EDch desti\u010Dek"@cs . "Administration of antipsychotics appears to be related to increased risk of venous thromboembolism and cerebrovascular side effects. The biological mechanism responsible for this possible adverse drug reaction is unknown, but there is a growing number of elucidating hypotheses. Treatment with antipsychotics is a asssociated with elevation of prolactin level. Prolactin has recently been recognized as potent platelet aggregation co-activator, and have therefore been postulated as an addditional risk factor for both arterial and venous thrombosis. We briefly review the arguments for the role of hyperprolactinemia in pathogenesis of platelet aggregation." . "Prolactin as a factor for increased platelet aggregation" . "5"^^ . "Pod\u00E1v\u00E1n\u00ED antipsychotik se zd\u00E1 b\u00FDt ve vztahu ke zv\u00FD\u0161en\u00E9mu riziku \u017Eiln\u00EDho tromboembolismu a cerebrovaskul\u00E1rn\u00EDm ne\u017E\u00E1douc\u00EDm \u00FA\u010Dink\u016Fm. Zat\u00EDm jsou biologick\u00E9 mechanismy t\u011Bchto ne\u017E\u00E1douc\u00EDch \u00FA\u010Dink\u016F nezn\u00E1m\u00E9. P\u0159i l\u00E9\u010Db\u011B antipsychotiky v\u0161ak vzr\u016Fst\u00E1 hladina prolaktinu. Prolaktin je koaktiv\u00E1torem sr\u00E1\u017Een\u00ED krevn\u00EDch desti\u010Dek. P\u0159edstavuje tedy rizikov\u00FD faktor pro arteri\u00E1ln\u00ED a \u017Eiln\u00ED tromb\u00F3zu. Kr\u00E1tce shrnujeme \u00FAdaje o roli hyperprolaktinemie v patogenezi sr\u00E1\u017Een\u00ED krevn\u00EDch desti\u010Dek."@cs . "[0E30A643391A]" . "101;106" . "Neuroendocrinology Letters" . . "28" . "Masopust, Ji\u0159\u00ED" . . "Mal\u00FD, Radovan" . "Urban, Ale\u0161" .