"Zad\u00E1k, Zden\u011Bk" . "CABI Publishing" . "Bl\u00E1ha, Vladim\u00EDr" . "Alfa-tokoferol u LDL-afer\u00E9zy"@cs . . "\u017D\u010F\u00E1nsk\u00FD, Petr" . "7"^^ . "978-1-84593-075-2" . "Alpha-tocopherol in lipoprotein apheresis" . "Prospective clinical study of the mutual interactions and particular role of fundamental lipid related atherogenic mechanisms in patients with severe hypercholesterolemia treated by low density lipoprotein apheresis. Project will investigate changes and correlation of the i) cholesterol biosynthetic pathway and its intermediary products, metabolism and absorption, ii) plasma and cell membrane unsaturated and saturated fatty acids. Futher examination will focus on iii) lipoperoxidation processes and antioxidant consumption. The results might improve our knowledge and thus treatment of atherosclerosis, which is the leading cause of morbidity and mortality in Czech Republic."@en . . "464629" . "Oxfordshire" . "Alpha-tocopherol in lipoprotein apheresis"@en . "RIV/00216208:11150/07:00003501" . "apoB; apolipoprotein B; HDL; high-density lipoprotein; IDL; intermediate-density lipoprotein; LDL; low-density lipoprotein; VLDL; very low-density lipoprotein"@en . "617;623" . "5"^^ . "Bl\u00E1ha, Milan" . . . . . "Alpha-tocopherol in lipoprotein apheresis"@en . . . "[D55EE69D8B3C]" . . "Alfa-tokoferol u LDL-afer\u00E9zy"@cs . . . "Prospective clinical study of the mutual interactions and particular role of fundamental lipid related atherogenic mechanisms in patients with severe hypercholesterolemia treated by low density lipoprotein apheresis. Project will investigate changes and correlation of the i) cholesterol biosynthetic pathway and its intermediary products, metabolism and absorption, ii) plasma and cell membrane unsaturated and saturated fatty acids. Futher examination will focus on iii) lipoperoxidation processes and antioxidant consumption. The results might improve our knowledge and thus treatment of atherosclerosis, which is the leading cause of morbidity and mortality in Czech Republic." . "4"^^ . . "RIV/00216208:11150/07:00003501!RIV08-MZ0-11150___" . "Alpha-tocopherol in lipoprotein apheresis" . . . . . . . "encyklopedie" . "Prospektivn\u00ED klinick\u00E1 studie vz\u00E1jemn\u00E9 interakce a \u00FAlohy nejd\u016Fle\u017Eit\u011Bj\u0161\u00EDch lipidov\u00FDch aterogenn\u00EDch mechanism\u016F u pacient\u016F se z\u00E1va\u017Enou hypercholesterol\u00E9mi\u00ED, l\u00E9\u010Den\u00FDch LDL (low density lipoprotein) afer\u00E9zou. Projekt, kter\u00FD navazuje na p\u0159edchoz\u00ED v\u00FDsledky \u0159e\u0161itelsk\u00E9ho t\u00FDmu, bude zkoumat zm\u011Bny a korelace n\u00E1sleduj\u00EDc\u00EDch parametr\u016F: i) biosynt\u00E9za cholesterolu a jeho intermedi\u00E1rn\u00EDch produkt\u016F. Dal\u0161\u00ED anal\u00FDza bude hodnotit ii) nenasycen\u00E9 a nasycen\u00E9 mastn\u00E9 kyseliny v plasm\u011B a bun\u011B\u010Dn\u00E9 membr\u00E1n\u011B, iii) pr\u016Fb\u011Bh lipoperoxidace a konsumpce antioxidant\u016F. Z\u00EDskan\u00E9 poznatky mohou p\u0159isp\u011Bt k objasn\u011Bn\u00ED a t\u00EDm i k l\u00E9\u010Db\u011B procesu ateroskler\u00F3zy, kter\u00E1 je nej\u010Dast\u011Bj\u0161\u00ED p\u0159\u00ED\u010Dinou morbidity a mortality v \u010Cesk\u00E9 republice."@cs . "11150" . . . "The Encyclopedia of Vitamin E" . . . . "P(NR8062)" . . .