. . "Idiopatick\u00FD hypereozinofiln\u00ED syndrom a chronick\u00E1 eozinofiln\u00ED leukemie (diferenci\u00E1ln\u00ED diagnoza a terapie ve sv\u011Btle nov\u00FDch poznatk\u016F)"@cs . "RIV/00216208:11150/06:00005005" . "11150" . . "Idiopatick\u00FD hypereozinofiln\u00ED syndrom a chronick\u00E1 eozinofiln\u00ED leukemie (diferenci\u00E1ln\u00ED diagnoza a terapie ve sv\u011Btle nov\u00FDch poznatk\u016F)" . "9"^^ . . "Idiopatick\u00FD hypereozinofiln\u00ED syndrom a chronick\u00E1 eozinofiln\u00ED leukemie (diferenci\u00E1ln\u00ED diagnoza a terapie ve sv\u011Btle nov\u00FDch poznatk\u016F)" . . "S" . "1385;1393" . . "Chrob\u00E1k, Ladislav" . "0042-773X" . . "12" . . . "RIV/00216208:11150/06:00005005!RIV08-MSM-11150___" . "Idiopatick\u00FD hypereozinofiln\u00ED syndrom (HES) je heterogenn\u00ED skupina hematologick\u00FDch stav\u016F charakterizovan\u00E1 eozinofili\u00ED (>1,5*109/1) p\u0159etrv\u00E1vaj\u00EDc\u00ED po dobu dels\u0161\u00ED ne\u017E 6 m\u011Bs\u00EDc\u016F, vylou\u010Den\u00EDm reaktivn\u00ED eozinofilie z jin\u00FDch p\u0159\u00ED\u010Din, jako parazit\u00E1rn\u00EDch onemocn\u011Bn\u00ED nebo alergie, a pr\u016Fkazem org\u00E1nov\u00E9ho po\u0161kozen\u00ED. je diskutov\u00E1na ot\u00E1zka rezistence na imatinib a mo\u017Enosti jej\u00EDho p\u0159ekon\u00E1n\u00ED p\u0159\u00ED l\u00E9\u010Db\u011B HES." . "Idiopatick\u00FD hypereozinofiln\u00ED syndrom a chronick\u00E1 eozinofiln\u00ED leukemie (diferenci\u00E1ln\u00ED diagnoza a terapie ve sv\u011Btle nov\u00FDch poznatk\u016F)"@cs . . "Idiopathic hypereosinophilic syndrome is a heterogenous group of hematological disorders characterized by eosinopholia (>1,5*109/1) persistent for more than 6 month, exclusion of reactive eosinophilia from other causes, such as parasitic infections or allergy, and evidence of end-organ damage. Other therapeutical options for HES/CEL have been mentioned. The resistence to imatinib and the possibilities how to overcome in treatment of HES it are discussed."@en . "2"^^ . "[779F22BB3DFF]" . . "1"^^ . . "Vnit\u0159n\u00ED l\u00E9ka\u0159stv\u00ED" . "Idiopatick\u00FD hypereozinofiln\u00ED syndrom (HES) je heterogenn\u00ED skupina hematologick\u00FDch stav\u016F charakterizovan\u00E1 eozinofili\u00ED (>1,5*109/1) p\u0159etrv\u00E1vaj\u00EDc\u00ED po dobu dels\u0161\u00ED ne\u017E 6 m\u011Bs\u00EDc\u016F, vylou\u010Den\u00EDm reaktivn\u00ED eozinofilie z jin\u00FDch p\u0159\u00ED\u010Din, jako parazit\u00E1rn\u00EDch onemocn\u011Bn\u00ED nebo alergie, a pr\u016Fkazem org\u00E1nov\u00E9ho po\u0161kozen\u00ED. je diskutov\u00E1na ot\u00E1zka rezistence na imatinib a mo\u017Enosti jej\u00EDho p\u0159ekon\u00E1n\u00ED p\u0159\u00ED l\u00E9\u010Db\u011B HES."@cs . . "idiopathic; hypereosinophilic; syndrome; chronic; eosinophilic; leukemia"@en . "The idiopathic hypereosinophilic syndrome and chronic eosinophilic leukemia"@en . . . "478786" . . . "The idiopathic hypereosinophilic syndrome and chronic eosinophilic leukemia"@en . "51" . "CZ - \u010Cesk\u00E1 republika" .