"521222" . . "48" . "11150" . . "5"^^ . "Liver cirhosis; Carbon tetrachloride; Hepatic stellate cells; Desmin; Glial fibrillary acidic protein; alpha-smooth muscle actin"@en . "Acta Medica (Hradec Kr\u00E1lov\u00E9)" . "1211-4286" . . "Expression of cytoskeletal proteins in hepatic stellate cells isolated from normal and cirrhotic rat liver" . . "RIV/00216208:11150/05:00003668" . . . . "RIV/00216208:11150/05:00003668!RIV06-MSM-11150___" . . "Jatern\u00ED hv\u011Bzdicov\u00E9 bu\u0148ky se nach\u00E1zej\u00ED v Disseho prostorech norm\u00E1ln\u00EDch jater. Ve fibrotick\u00FDch j\u00E1trech se aktivuj\u00ED, proliferuj\u00ED a p\u0159em\u011B\u0148uj\u00ED se na bu\u0148ky podobn\u00E9 myofibroblast\u016Fm. Zm\u011Bny fenotypu jsou prov\u00E1zeny zm\u011Bnami bun\u011B\u010Dn\u00E9ho cytoskeletu. Studovali jsme zm\u011Bny hladkosvalov\u00E9ho alfa-aktinu, desminu, vimentinu a GFAP v bu\u0148k\u00E1ch izolovan\u00FDch z norm\u00E1ln\u00EDch i cirhotick\u00FDch jater."@cs . . . "Expression of cytoskeletal proteins in hepatic stellate cells isolated from normal and cirrhotic rat liver"@en . "Exprese b\u00EDlkovin cytoskeletu v jatern\u00EDch hv\u011Bzdicov\u00FDch bu\u0148k\u00E1ch izolovan\u00FDch z norm\u00E1ln\u00EDch a cirhotick\u00FDch jater"@cs . "Hepatic stellate cells (HSC) are located in Disse spaces of normal rat liver. In fibrotic liver they become activated, proliferate and they undergo transdifferentiation into myofibroblast-like cells. Changes in the cell phenotype are accompanied by changes in the cellular cytoskeleton. We have studied the expression of alpha-smooth muscle actin and intermediate filament proteins vimentin, desmin and glial fibrillary acidic protein (GFAP) by immunocytochemistry in HSC cultured for 2 or 7 days after isolation. HSC were isolated from normal or CCl4-cirrhotic rat liver."@en . . . "CZ - \u010Cesk\u00E1 republika" . "Exprese b\u00EDlkovin cytoskeletu v jatern\u00EDch hv\u011Bzdicov\u00FDch bu\u0148k\u00E1ch izolovan\u00FDch z norm\u00E1ln\u00EDch a cirhotick\u00FDch jater"@cs . "P(GA305/03/1513), Z(MSM0021620820)" . "Kanta, Ji\u0159\u00ED" . "137;144" . "Expression of cytoskeletal proteins in hepatic stellate cells isolated from normal and cirrhotic rat liver"@en . "8"^^ . . . "3" . . . . . "2"^^ . "K\u00F6hlerov\u00E1, Renata" . "[63CE27E2D379]" . "Hepatic stellate cells (HSC) are located in Disse spaces of normal rat liver. In fibrotic liver they become activated, proliferate and they undergo transdifferentiation into myofibroblast-like cells. Changes in the cell phenotype are accompanied by changes in the cellular cytoskeleton. We have studied the expression of alpha-smooth muscle actin and intermediate filament proteins vimentin, desmin and glial fibrillary acidic protein (GFAP) by immunocytochemistry in HSC cultured for 2 or 7 days after isolation. HSC were isolated from normal or CCl4-cirrhotic rat liver." . "Expression of cytoskeletal proteins in hepatic stellate cells isolated from normal and cirrhotic rat liver" . . . .