. "1"^^ . . "[AE04AD65C198]" . . "RIV/00216208:11150/04:00002110" . . . "Metabolismus b\u00EDlkovin v kostern\u00EDm svalu, zm\u011Bny p\u0159i sepsi a mo\u017Enosti ovlivn\u011Bn\u00ED"@cs . "1"^^ . "Metabolismus b\u00EDlkovin v kostern\u00EDm svalu, zm\u011Bny p\u0159i sepsi a mo\u017Enosti ovlivn\u011Bn\u00ED" . "Metabolismus b\u00EDlkovin v kostern\u00EDm svalu, zm\u011Bny p\u0159i sepsi a mo\u017Enosti ovlivn\u011Bn\u00ED"@cs . "Univerzita Karlova v Praze. L\u00E9ka\u0159sk\u00E1 fakulta v Hradci Kr\u00E1lov\u00E9" . "Hradec Kr\u00E1lov\u00E9" . "The aim of our studies was to evaluate the effect of acidosis and sepsis on protein metabolism and the effect of glutamine, growth hormone and their combination in septic state. All parameters were measured in rats, either in vivo, in perfused liver, or incubated skeletal muscles. Sepsis had a negative effect on protein and amino acid metabolism that had not been prevented by administration of growth hormone. Supplementation of glutamine had a favorable effect on metabolism of branched-chain amino acids. Acidosis resulted in negative protein balance with increased protein turnover."@en . "C\u00EDlem na\u0161ich studi\u00ED bylo zm\u011B\u0159it vliv acid\u00F3zy a sepse na metabolismus b\u00EDlkovin a posoudit jeho ovlivn\u011Bn\u00ED glutaminem, r\u016Fstov\u00FDm hormonem a jejich kombinac\u00ED. Parametry byly m\u011B\u0159eny na potkanech in vivo, v perfundovan\u00FDch j\u00E1trech a inkubovan\u00FDch kostern\u00EDch svalech. Sepse m\u011Bla nep\u0159\u00EDzniv\u00FD vliv na metabolismus b\u00EDlkovin a aminokyselin, kter\u00FD nebylo mo\u017En\u00E9 zm\u00EDrnit pod\u00E1v\u00E1n\u00EDm r\u016Fstov\u00E9ho hormonu. Suplementace glutaminem m\u011Bla p\u0159\u00EDzniv\u00FD \u00FA\u010Dinek na metabolismus aminokyselin s rozv\u011Btven\u00FDm \u0159et\u011Bzcem. Acid\u00F3za zvy\u0161ovala obrat b\u00EDlkovin a vedla k negativn\u00ED dus\u00EDkov\u00E9 bilanci." . . . . "Nov\u00E9 v\u00FDzkumn\u00E9 sm\u011Bry v doktorandsk\u00FDch prac\u00EDch l\u00E9ka\u0159sk\u00FDch fakult. 1. Kr\u00E1lovehradeck\u00E9 l\u00E9ka\u0159sk\u00E9 postgradu\u00E1ln\u00ED dny" . "Protein metabolism in isolated skeletal muscle in sepsis and its modulation"@en . "metabolism;protein;sepsis;skeletal muscle"@en . . "RIV/00216208:11150/04:00002110!RIV/2005/MZ0/111505/N" . . "Protein metabolism in isolated skeletal muscle in sepsis and its modulation"@en . . . "Metabolismus b\u00EDlkovin v kostern\u00EDm svalu, zm\u011Bny p\u0159i sepsi a mo\u017Enosti ovlivn\u011Bn\u00ED" . "80-239-3990-4" . "573027" . . "\u0160afr\u00E1nek, Roman" . . . "11150" . "P(NB7611)" . "89;91" . . "C\u00EDlem na\u0161ich studi\u00ED bylo zm\u011B\u0159it vliv acid\u00F3zy a sepse na metabolismus b\u00EDlkovin a posoudit jeho ovlivn\u011Bn\u00ED glutaminem, r\u016Fstov\u00FDm hormonem a jejich kombinac\u00ED. Parametry byly m\u011B\u0159eny na potkanech in vivo, v perfundovan\u00FDch j\u00E1trech a inkubovan\u00FDch kostern\u00EDch svalech. Sepse m\u011Bla nep\u0159\u00EDzniv\u00FD vliv na metabolismus b\u00EDlkovin a aminokyselin, kter\u00FD nebylo mo\u017En\u00E9 zm\u00EDrnit pod\u00E1v\u00E1n\u00EDm r\u016Fstov\u00E9ho hormonu. Suplementace glutaminem m\u011Bla p\u0159\u00EDzniv\u00FD \u00FA\u010Dinek na metabolismus aminokyselin s rozv\u011Btven\u00FDm \u0159et\u011Bzcem. Acid\u00F3za zvy\u0161ovala obrat b\u00EDlkovin a vedla k negativn\u00ED dus\u00EDkov\u00E9 bilanci."@cs . "3"^^ .