. "Koment\u00E1\u0159 k technice microarray"@cs . . "[B340887092BB]" . "Microarray; technic"@en . "4" . . "Koment\u00E1\u0159 k technice microarray" . . . "11150" . "CZ - \u010Cesk\u00E1 republika" . "Alergie" . "Koment\u00E1\u0159 k technice microarray" . . . "331;332" . . "612402" . "S" . . "Microarray technic"@en . . "Microarray technic"@en . . "Koment\u00E1\u0159 k technice microarray"@cs . . "2"^^ . . "1"^^ . "Genome analysis provides information about the number of gene copies and presence of differences in particular bases comprising the primary sequence of DNA. Hereditary transfer of changes of particular bases is called genome polymorphism. If the changes in the particular bases occur during the life, they are characterised as mutations. Estimation is that in humans there are about 900 genes exhibiting polymorphism, which results in production of proteins with altered function."@en . "1212-3536" . "Genomov\u00E1 anal\u00FDza poskytuje informaci o po\u010Dtu genov\u00FDch kopi\u00ED a o p\u0159\u00EDtomnosti rozd\u00EDl\u016F v jednotliv\u00FDch b\u00E1z\u00EDch tvo\u0159\u00EDc\u00EDch prim\u00E1rn\u00ED sekvenci DNA. D\u011Bdi\u010Dn\u011B p\u0159ed\u00E1van\u00E9 zm\u011Bny jednotliv\u00FDch b\u00E1z\u00ED jsou ozna\u010Dov\u00E1ny jako genov\u00FD polymorfismus. Pokud ke zm\u011Bn\u00E1m jednotliv\u00FDch nukleotidov\u00FDch b\u00E1z\u00ED dojde v pr\u016Fb\u011Bhu \u017Eivota, jsou ozna\u010Dov\u00E1ny jako mutace. Odhaduje se, \u017Ee u \u010Dlov\u011Bka existuje okolo 900 gen\u016F vykazuj\u00EDc\u00EDch polymorfismus, kter\u00FD v d\u016Fsledku vede k tvorb\u011B protein\u016F se zm\u011Bn\u011Bnou funkc\u00ED."@cs . "5" . "RIV/00216208:11150/03:00004382" . "Krejsek, Jan" . "RIV/00216208:11150/03:00004382!RIV08-MSM-11150___" . "1"^^ . "Genomov\u00E1 anal\u00FDza poskytuje informaci o po\u010Dtu genov\u00FDch kopi\u00ED a o p\u0159\u00EDtomnosti rozd\u00EDl\u016F v jednotliv\u00FDch b\u00E1z\u00EDch tvo\u0159\u00EDc\u00EDch prim\u00E1rn\u00ED sekvenci DNA. D\u011Bdi\u010Dn\u011B p\u0159ed\u00E1van\u00E9 zm\u011Bny jednotliv\u00FDch b\u00E1z\u00ED jsou ozna\u010Dov\u00E1ny jako genov\u00FD polymorfismus. Pokud ke zm\u011Bn\u00E1m jednotliv\u00FDch nukleotidov\u00FDch b\u00E1z\u00ED dojde v pr\u016Fb\u011Bhu \u017Eivota, jsou ozna\u010Dov\u00E1ny jako mutace. Odhaduje se, \u017Ee u \u010Dlov\u011Bka existuje okolo 900 gen\u016F vykazuj\u00EDc\u00EDch polymorfismus, kter\u00FD v d\u016Fsledku vede k tvorb\u011B protein\u016F se zm\u011Bn\u011Bnou funkc\u00ED." .