. "Mosel, D. D." . . "2"^^ . "Cetkovsk\u00E1, Petra" . "Pain Identifies Squamous Cell Carcinoma in Organ Transplant Recipients: The SCOPE-ITSCC PAIN Study"@en . "G\u00FClec, A. T." . "000331783200022" . . "American Journal of Transplantation" . "Jahn, K." . "Imko-Walczuk, B." . "Plasmeijer, E. I." . "I" . . "Hofbauer, G. F. L." . "3" . "Conzett, K. B." . "DK - D\u00E1nsk\u00E9 kr\u00E1lovstv\u00ED" . "35601" . "RIV/00216208:11140/14:10192707!RIV15-MSM-11140___" . . . . . "Seckin, D." . . "Wisgerhof, H. C." . "Pokorney, M. S." . "Mitchell, L." . . "24"^^ . "Piaserico, S." . "Pain Identifies Squamous Cell Carcinoma in Organ Transplant Recipients: The SCOPE-ITSCC PAIN Study" . "11140" . "Feldmeyer, L." . "Geusau, A." . "Genders, R. E." . "Bavinck, J. N. B." . "Olasz, E. B." . "10.1111/ajt.12587" . "Pain Identifies Squamous Cell Carcinoma in Organ Transplant Recipients: The SCOPE-ITSCC PAIN Study"@en . "Organ transplant recipients (OTR) are at high risk for cutaneous squamous cell carcinomas (SCC). We aimed to define clinically meaningful patient-reported warning signals predicting the presence of invasive SCC. Patient-reported signs and symptoms of 812 consecutively biopsied skin lesions from 410 OTR were determinde by questionnaire and physical examination and related to the subsequent biopsy-proven diagnoses. Receiver-operating characteristic (ROC) curve analyses were used as a measure of distinction between the predictive values of patient-reported warning signals and the occurrence of SCC. Pain was an independent predictive patient-reported warning signal for a biopsy-proven invasive SCC. The odds ratio from the fully adjusted model predicting SCC was 4.4 (95% confidence interval: 2.4-8.2). Higher scores on the visual analog scale (VAS) for pain were associated with a greater likelihood for the presence of SCC compared to none or mild pain. The for scores on the VAS from 1 to 3, 4 to 6 and 7 to 10 were 4.9 (2.2-10-5), 2.3 (0,96-5.5) and 16.5 (3.6-75.8), respectively. Pain is the most powerful patient-reported warning signal for invasive cutaneous SCC in OTR. Empowerment of patients by education could accelerate diagnosis and treatment of cutaneous SCC."@en . "Harwood, C. A." . "1600-6135" . "Serra, A. L." . . "[3A2C0CF4AACB]" . "Proby, C. M." . "14" . "Fortina, A. B." . . . "Pain Identifies Squamous Cell Carcinoma in Organ Transplant Recipients: The SCOPE-ITSCC PAIN Study" . "Gerritsen, M. J. P." . "9"^^ . "Organ transplant recipients (OTR) are at high risk for cutaneous squamous cell carcinomas (SCC). We aimed to define clinically meaningful patient-reported warning signals predicting the presence of invasive SCC. Patient-reported signs and symptoms of 812 consecutively biopsied skin lesions from 410 OTR were determinde by questionnaire and physical examination and related to the subsequent biopsy-proven diagnoses. Receiver-operating characteristic (ROC) curve analyses were used as a measure of distinction between the predictive values of patient-reported warning signals and the occurrence of SCC. Pain was an independent predictive patient-reported warning signal for a biopsy-proven invasive SCC. The odds ratio from the fully adjusted model predicting SCC was 4.4 (95% confidence interval: 2.4-8.2). Higher scores on the visual analog scale (VAS) for pain were associated with a greater likelihood for the presence of SCC compared to none or mild pain. The for scores on the VAS from 1 to 3, 4 to 6 and 7 to 10 were 4.9 (2.2-10-5), 2.3 (0,96-5.5) and 16.5 (3.6-75.8), respectively. Pain is the most powerful patient-reported warning signal for invasive cutaneous SCC in OTR. Empowerment of patients by education could accelerate diagnosis and treatment of cutaneous SCC." . . . "RIV/00216208:11140/14:10192707" . "\u0158\u00ED\u010Da\u0159, Jan" . "squamous cell carcinoma; pain; Adverse affect"@en .