. . . "6"^^ . "Is there any relationship between cytokine spectrum of breast milk and occurence of eosinophilic colitis?"@en . . . "Acta Paediatrica" . . . "\u0160techov\u00E1, Kate\u0159ina" . . . . "99" . "000282641600013" . . . "RIV/00216208:11130/10:6341!RIV11-MZ0-11130___" . "RIV/00216208:11130/10:6341" . . "Durilov\u00E1, Marianna" . "[E166DB261A10]" . . "I, P(NR8310)" . . "5"^^ . "Aim: The aim of our study was to analyse cytokine composition of human milk and its relationship to the development of eosinophilic colitis (EC). Methods: Cytokines were measured by ELISA method in breast milk of 20 mothers of infants who developed EC and 20 controls. Results: We found significantly higher concentrations of interferon-gamma (IFN-gamma) (Th1 cytokine) in breast milk received by EC infants compared to controls (p = 0.0004). In contrary, IL-18 (Th1-inducing cytokine) was significantly higher in breast milk received by healthy infants comparing to EC infants (p = 0.001). Regulatory cytokine transforming growth factor beta1 (TGF-beta1) showed higher concentrations in breast milk received by healthy infants, although the difference from EC group was not significant (p = 0.072). Conclusion: The results of our study showed that infants with EC were receiving breast milk with a possibly risky cytokine pattern indicating cytokine imbalance, impaired immunoregulation and the early Th1 shift." . . . "Nevoral, Ji\u0159\u00ED" . . "breast milk; cytokine; eosinophilic colitis"@en . . "NO - Norsk\u00E9 kr\u00E1lovstv\u00ED" . "Is there any relationship between cytokine spectrum of breast milk and occurence of eosinophilic colitis?" . "\u0160\u0165av\u00EDkov\u00E1, Vendula" . . "Ulmannov\u00E1, Tereza" . "Is there any relationship between cytokine spectrum of breast milk and occurence of eosinophilic colitis?" . "0803-5253" . "Petru\u017Eelkov\u00E1, Lenka" . "264983" . "11130" . "Aim: The aim of our study was to analyse cytokine composition of human milk and its relationship to the development of eosinophilic colitis (EC). Methods: Cytokines were measured by ELISA method in breast milk of 20 mothers of infants who developed EC and 20 controls. Results: We found significantly higher concentrations of interferon-gamma (IFN-gamma) (Th1 cytokine) in breast milk received by EC infants compared to controls (p = 0.0004). In contrary, IL-18 (Th1-inducing cytokine) was significantly higher in breast milk received by healthy infants comparing to EC infants (p = 0.001). Regulatory cytokine transforming growth factor beta1 (TGF-beta1) showed higher concentrations in breast milk received by healthy infants, although the difference from EC group was not significant (p = 0.072). Conclusion: The results of our study showed that infants with EC were receiving breast milk with a possibly risky cytokine pattern indicating cytokine imbalance, impaired immunoregulation and the early Th1 shift."@en . "6"^^ . "11" . "Is there any relationship between cytokine spectrum of breast milk and occurence of eosinophilic colitis?"@en . .