"flow cytometry; endometrial carcinoma; heterogeneity; DNA ploidy"@en . "Pint\u00E9rov\u00E1, Daniela" . . . "Tikovsk\u00FD, Karel" . "138866" . . "Aim: Comparison of DNA ploidy status of different tumour tissue samples (fresh/frozen vs. paraffin-embedded; curettage vs. hysterectomy samples) obtained during diagnosis and treatment of patients with endometrial carcinoma. Patients and Methods: DNA ploidy status and conventional prognostic parameters were recorded for 74 patients with endometrial carcinoma prospectively. Results: In 59 (79.7%) patients the DNA status was described as diploid in all analyzed tissue samples. The remaining 15 (20.3%) cases were described as DNA aneuploid in at least one of the corresponding tissue samples. The concordance between DNA ploidy status in fresh vs. paraffin-embedded hysterectomy samples as well as curettage vs. hysterectomy paraffin-embedded samples was high (kappa coefficient \u03BA=0.6348, 95% confidence interval CI=0.3673-0.9023, and p=0.6408, 95% CI=0.3977-0.8838), however, the methods are not interchangeable. Conclusion: The DNA ploidy discordance observed in our study group seems to document intratumoral heterogeneity that should be expected when applying DNA ploidy status in the clinical management of endometrial carcinoma."@en . . . "P(NS9975)" . "http://iv.iiarjournals.org/content/26/3/473.abstract" . . . "Hubi\u010Dkov\u00E1 Heringov\u00E1, Lucie" . "In Vivo" . . . . . "3" . . . "000303351100018" . "Kolo\u0161tov\u00E1, Katar\u00EDna" . . . . "GR - \u0158eck\u00E1 republika" . . "11"^^ . "0258-851X" . . . "8"^^ . "L\u00EDbalov\u00E1, Pavla" . "26" . "Heterogeneity of DNA Ploidy in Endometrial Carcinoma: Comparison of Different Tissue Samples Obtained during Diagnosis and Treatment"@en . . "Svoboda, Bohuslav" . "Kubecov\u00E1, Martina" . . "11120" . . "Housa, Daniel" . "Vernerov\u00E1, Zde\u0148ka" . . "10"^^ . "RIV/00216208:11120/12:43903600!RIV13-MZ0-11120___" . "Heterogeneity of DNA Ploidy in Endometrial Carcinoma: Comparison of Different Tissue Samples Obtained during Diagnosis and Treatment" . "Heterogeneity of DNA Ploidy in Endometrial Carcinoma: Comparison of Different Tissue Samples Obtained during Diagnosis and Treatment"@en . "[C648D215D726]" . . "Bobek, Vladim\u00EDr" . . "Heterogeneity of DNA Ploidy in Endometrial Carcinoma: Comparison of Different Tissue Samples Obtained during Diagnosis and Treatment" . "Aim: Comparison of DNA ploidy status of different tumour tissue samples (fresh/frozen vs. paraffin-embedded; curettage vs. hysterectomy samples) obtained during diagnosis and treatment of patients with endometrial carcinoma. Patients and Methods: DNA ploidy status and conventional prognostic parameters were recorded for 74 patients with endometrial carcinoma prospectively. Results: In 59 (79.7%) patients the DNA status was described as diploid in all analyzed tissue samples. The remaining 15 (20.3%) cases were described as DNA aneuploid in at least one of the corresponding tissue samples. The concordance between DNA ploidy status in fresh vs. paraffin-embedded hysterectomy samples as well as curettage vs. hysterectomy paraffin-embedded samples was high (kappa coefficient \u03BA=0.6348, 95% confidence interval CI=0.3673-0.9023, and p=0.6408, 95% CI=0.3977-0.8838), however, the methods are not interchangeable. Conclusion: The DNA ploidy discordance observed in our study group seems to document intratumoral heterogeneity that should be expected when applying DNA ploidy status in the clinical management of endometrial carcinoma." . . "RIV/00216208:11120/12:43903600" .