"Multimarker real-time reverse transcription-PCR for quantitative detection of melanoma-associated antigens: a novel possible staging method"@en . "Multimarker real-time reverse transcription-PCR for quantitative detection of melanoma-associated antigens: a novel possible staging method" . . "6"^^ . "Arenberger, Petr" . "0926-9959" . . "P(1A8243)" . "1" . "Gkalpakiotis, Spyridon" . . . . . . . . "RIV/00216208:11120/08:00001334" . "9"^^ . . "Multimarkerov\u00E1 RT-PCR v re\u00E1ln\u00E9m \u010Dase pro kvantitativn\u00ED detekci melanomov\u00FDch antigen\u016F: nov\u00E9 mo\u017Enosti stagingu"@cs . . "detection; circulating melanoma cells; malignant melanoma; melanoma markers; real-time RT-PCR"@en . . "Gkalpakiotis, Spyridon" . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . "11120" . "Multimarker real-time reverse transcription-PCR for quantitative detection of melanoma-associated antigens: a novel possible staging method"@en . "[6155E2F46A0E]" . . . "Multimarkerov\u00E1 RT-PCR v re\u00E1ln\u00E9m \u010Dase pro kvantitativn\u00ED detekci melanomov\u00FDch antigen\u016F: nov\u00E9 mo\u017Enosti stagingu"@cs . "St\u0159\u00EDbrn\u00E1, Jana" . "Arenbergerov\u00E1, Monika" . "Journal of the European Academy of Dermatology and Venereology" . "3"^^ . "Detection of melanoma cells in peripheral blood is a promising method for monitoring haematogenous spread of melanoma cells. It enables us to detect early metastasis and to better stratify candidates for adjuvant immunotherapy. Inconsistent data on the sensitivity and clinical relevance of this method have been reported." . "RIV/00216208:11120/08:00001334!RIV09-MZ0-11120___" . "K\u0159emen, Jarom\u00EDr" . . "Detekce melanomov\u00FDch bun\u011Bk z perifern\u00ED krve je slibnou metodou k monitoringu diseminace n\u00E1dorov\u00FDch bun\u011Bk krevn\u00ED cestou a tedy k v\u010Dasn\u00E9mu rozpozn\u00E1n\u00ED metast\u00E1z. V t\u00E9to pr\u00E1ci je popisov\u00E1na multimarkerov\u00E1 real-time RT-PCR, kterou auto\u0159i pro tyto \u00FA\u010Dely \u00FAsp\u011B\u0161n\u011B etablovali. Kvantitativn\u011B bylo z perifern\u00ED krve stanoveno 5 marker\u016F melanomov\u00FDch bun\u011Bk: Melan-A/MART-1, gp 100, MAGE-3, MIA a tyrozin\u00E1za. V t\u00E9to prospektivn\u00ED studii byl proveden screening 65 pacient\u016F po resekci rizikov\u00E9ho ko\u017En\u00EDho melanomu. Zjistilo se, \u017Ee kvantitativn\u00ED detekce melanomov\u00FDch marker\u016F je spolehliv\u00E1 a u\u017Eite\u010Dn\u00E1 metoda k v\u010Dasn\u00E9mu rozpozn\u00E1n\u00ED hematogenn\u00EDho rozsevu u melanomov\u00FDch pacient\u016F. Tato metoda m\u016F\u017Ee slou\u017Eit jako d\u016Fle\u017Eit\u00FD prognostick\u00FD faktor a v budoucnu se m\u016F\u017Ee uplatnit p\u0159i screeningu rizikov\u00FDch pacient\u016F a k monitoringu \u00FAsp\u011B\u0161nosti terapie"@cs . "22" . "Detection of melanoma cells in peripheral blood is a promising method for monitoring haematogenous spread of melanoma cells. It enables us to detect early metastasis and to better stratify candidates for adjuvant immunotherapy. Inconsistent data on the sensitivity and clinical relevance of this method have been reported."@en . . "Multimarker real-time reverse transcription-PCR for quantitative detection of melanoma-associated antigens: a novel possible staging method" . "Lippert, Jan" . "381139" . "000251811000010" . . .