. . "1"^^ . . . "Fetal Pain" . "367872" . "fetal pain and nociception; development of pain perception; fetal analgesia"@en . "RIV/00216208:11120/08:00000914" . "Fet\u00E1ln\u00ED bolest"@cs . "1"^^ . . . "Fetal Pain"@en . . "Fetal Pain"@en . . . "P(1M0517), P(LC554), Z(MSM0021620816)" . "000263044200001" . . "[0BD4D80DABBC]" . "0172-780X" . . "Neuroendocrinology Letters" . "11120" . . "The fetus reacts to nociceptive stimulations through different motor, autonomic vegetative hormonal and metabolic changes in relatively early gestational period. With respect to the fact that does not yet exist the modulatory system, the first reactions are purely reflexive and without connection to the type of stimulus. While the fetal nervous system is able to react through protective reflexes against eventual deteriorating noxa, it does not exist an accurate evidence concerning pain sensations in this early period. The cortical processes occur only after the thalamocortical connections and pathways have been terminated at the 26th gestation al week. The painful deteriorating stimuli, especially in fetuses have an aversive effect on the development of human disregard in the processes in brain. Moreover, the pain activates the quantity of subcortical mechanisms and a large spectrum of stress responses which influence the maturation of thalamocortical pathways and of other cortical activation which ar" . "Rokyta, Richard" . "Fetus reaguje na nociceptivn\u00ED stimulaci r\u016Fzn\u00FDmi motorick\u00FDmi, autonomn\u00EDmi (vegetativn\u00EDmi), hormon\u00E1ln\u00EDmi a metabolick\u00FDmi zm\u011Bnami relativn\u011B brzo v t\u011Bhotenstv\u00ED. Vzhledem k tomu, \u017Ee nen\u00ED je\u0161t\u011B vyvinut modula\u010Dn\u00ED syst\u00E9m, jsou prvn\u00ED reakce \u010Dist\u011B reflexn\u00ED a nez\u00E1vis\u00ED na typu podn\u011Btu. Proto\u017Ee fet\u00E1ln\u00ED nervov\u00FD syst\u00E9m je schopen reagovat obrann\u00FDmi reflexy na potenci\u00E1ln\u011B nebezpe\u010Dn\u00E9 podn\u011Bty, nen\u00ED p\u0159esn\u00E1 evidence t\u00FDkaj\u00EDc\u00ED vn\u00EDm\u00E1n\u00ED bolesti v t\u011Bchto rann\u00FDch obdob\u00EDch. Korov\u00E9 procesy za\u010D\u00EDnaj\u00ED po dokon\u010Den\u00ED talamokortik\u00E1ln\u00EDch spojen\u00ED ve 26. gesta\u010Dn\u00EDm t\u00FDdnu. Bolest aktivuje tak\u00E9 mnoho subkortik\u00E1ln\u00EDch mechanism\u016F a objevuje se \u0161irok\u00E9 spektrum stresov\u00FDch odpov\u011Bd\u00ED, kter\u00E9 ovliv\u0148uj\u00ED dozr\u00E1v\u00E1n\u00ED talamokortik\u00E1ln\u00EDch drah a dal\u0161\u00EDch korov\u00E9 aktivace, kter\u00E9 jsou velmi d\u016Fle\u017Eit\u00E9 ve vytv\u00E1\u0159\u00EDen\u00ED bolestiv\u00E9ho vn\u00EDm\u00E1n\u00ED."@cs . "RIV/00216208:11120/08:00000914!RIV09-MSM-11120___" . "Fetal Pain" . "8"^^ . "Fet\u00E1ln\u00ED bolest"@cs . . . . . "The fetus reacts to nociceptive stimulations through different motor, autonomic vegetative hormonal and metabolic changes in relatively early gestational period. With respect to the fact that does not yet exist the modulatory system, the first reactions are purely reflexive and without connection to the type of stimulus. While the fetal nervous system is able to react through protective reflexes against eventual deteriorating noxa, it does not exist an accurate evidence concerning pain sensations in this early period. The cortical processes occur only after the thalamocortical connections and pathways have been terminated at the 26th gestation al week. The painful deteriorating stimuli, especially in fetuses have an aversive effect on the development of human disregard in the processes in brain. Moreover, the pain activates the quantity of subcortical mechanisms and a large spectrum of stress responses which influence the maturation of thalamocortical pathways and of other cortical activation which ar"@en . "29" . . "SE - \u0160v\u00E9dsk\u00E9 kr\u00E1lovstv\u00ED" . . "6" .