"Jur\u010Dovi\u010Dov\u00E1, Jana" . . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . "RIV/00216208:11120/08:00000910" . . "Pometlov\u00E1, Marie" . "0172-8172" . . "Z(MSM0021620816)" . . . . "\u00DAzkost a deprese se obvykle objevuj\u00ED v patologii revmatick\u00FDch onemocn\u011Bn\u00ED. Pom\u011Brn\u011B m\u00E1lo se v\u00ED o vlivu z\u00E1n\u011Btliv\u00E9ho procesu na celkovou aktivitu v po\u010D\u00E1te\u010Dn\u00ED, bezp\u0159\u00EDznakov\u00E9 f\u00E1zi. C\u00EDlem studie bylo studovat \u00FAzkostliv\u00E9 chov\u00E1n\u00ED v po\u010D\u00E1te\u010Dn\u00E9 f\u00E1zi adjuvantn\u00ED artritidy (AA) u samc\u016F a samic potkan\u016F kmene Long Evans, jako i ed\u00E9m a hladiny kortikosteronu v klinick\u00E9 f\u00E1zi AA. K vyhodnocen\u00ED aspekt\u016F chov\u00E1n\u00ED bylo pou\u017Eito testu zv\u00FD\u0161en\u00E9ho bludi\u0161t\u011B tvaru k\u0159\u00ED\u017Ee. Na \u010Dtvrt\u00FD den AA se u artritick\u00FDch samc\u016F signifikantn\u011B sn\u00ED\u017Eil po\u010Det vstup\u016F do otev\u0159en\u00E9ho ramena. U samic k t\u011Bmto zm\u011Bn\u00E1m nedo\u0161lo. Jednotliv\u00E1 pohlav\u00ED se od sebe neli\u0161ila po\u010Dtem vstup\u016F do ramena zav\u0159en\u00E9ho. U artritick\u00FDch samc\u016F \u010Das str\u00E1ven\u00FD v otev\u0159en\u00E9m rameni signifikantn\u011B poklesl, inverzn\u011B k \u010Dasu str\u00E1ven\u00E9mu v zav\u0159en\u00E9m rameni. Na 23. den AA hladina kortikosteronu v plasm\u011B vzrostla stejn\u011B u obou pohlav\u00ED. Velikost\u00ED ed\u00E9mu se pohlav\u00ED neli\u0161ila. Z v\u00FDsledk\u016F vypl\u00FDv\u00E1, \u017Ee se v rann\u00ED f\u00E1ze AA (na \u010Dtvrt\u00FD den) u artritick\u00FDch samc\u016F objevily zn\u00E1mky \u00FAzkostliv\u00E9ho chov\u00E1n\u00ED, co nazna\u010Duje o"@cs . . "Anxiety and depression commonly occur in the pathology of rheumatic diseases. Little is known about how inflammatory disease in its early stage, before any clinical manifestation, may affect general activity. The aim of this study was to compare the anxiety-like behaviour in the early stage of adjuvant arthritis (AA), and the paw edema, and corticosterone (CORT) levels in the developed stage of AA among male and female Long Evans rats. The behavioural activity was evaluated by elevated plus maze tests. These revealed significantly reduced number of entries into the open arm of the maze in arthritic males compared to controls or to females 4 days after AA induction. Arthrihtic and control females did not differ. The number of entries into the closed arm of the maze was the same across the genders and studied intervals. Time spent in the open arm was significantly lower in arthritic males against controls or arthitic females. Time spent in the closed arm showed inverse picture to the time spent in the o" . . "9" . . "Roman, Olga" . "Early stage of adjuvant arthritis alters behavioral responses in male but not female rats"@en . . "Anxiety and depression commonly occur in the pathology of rheumatic diseases. Little is known about how inflammatory disease in its early stage, before any clinical manifestation, may affect general activity. The aim of this study was to compare the anxiety-like behaviour in the early stage of adjuvant arthritis (AA), and the paw edema, and corticosterone (CORT) levels in the developed stage of AA among male and female Long Evans rats. The behavioural activity was evaluated by elevated plus maze tests. These revealed significantly reduced number of entries into the open arm of the maze in arthritic males compared to controls or to females 4 days after AA induction. Arthrihtic and control females did not differ. The number of entries into the closed arm of the maze was the same across the genders and studied intervals. Time spent in the open arm was significantly lower in arthritic males against controls or arthitic females. Time spent in the closed arm showed inverse picture to the time spent in the o"@en . "Early stage of adjuvant arthritis alters behavioral responses in male but not female rats" . . . . "Early stage of adjuvant arthritis alters behavioral responses in male but not female rats" . "000256474800007" . "28" . "\u0160kurlov\u00E1, Martina" . . "Inici\u00E1ln\u00ED f\u00E1ze adjuvantn\u00ED artritidy m\u011Bn\u00ED prvky chov\u00E1n\u00ED u samc\u016F, ale nikoliv u samic potkan\u016F"@cs . "4"^^ . "6"^^ . "[626B9BAC3CDA]" . "Early stage of adjuvant arthritis alters behavioral responses in male but not female rats"@en . "Inici\u00E1ln\u00ED f\u00E1ze adjuvantn\u00ED artritidy m\u011Bn\u00ED prvky chov\u00E1n\u00ED u samc\u016F, ale nikoliv u samic potkan\u016F"@cs . . "Adjuvant arthritis; Male rats; Female rats; Emotional stress; Behaviour"@en . "Rheumatology International" . "Seres-Mailo, Janette" . "RIV/00216208:11120/08:00000910!RIV09-MSM-11120___" . . . . "\u0160tofkov\u00E1, Andrea" . "11120" . . "6"^^ . "364765" . .