"High prevalence of HFE gene mutations in patients with porphyria cutanea tarda in the Czech Republic"@en . . "Hor\u00E1k, Ji\u0159\u00ED" . "chronic hepatitis C; haemochromatosis; HFE gene; porphyria cutanea tarda; TFR2 gene"@en . "Str\u00E1nsk\u00FD, Jaroslav" . "159" . "370059" . . "[9FB5C80C3BC9]" . . "The aim of the study was to determine the prevalence of mutations in the HFE and TFR2 genes together with HCV infection in patients with porphyria cutanea tarda in the Czech population, and to make comparison of the iron status among the respective genotypes. There was a very high prevalence of the C282Y and H63D mutations observed in patients with PCT accompanied by mild degrees of iron overload, which was genotype dependent."@en . . "C\u00EDlem pr\u00E1ce bylo zjistit prevalenci mutac\u00ED v genech HFE a TFR2, HCV infekci u pacient\u016F s porphyria cutanea tarda v \u010Desk\u00E9 populaci, a parametry metabolismu \u017Eeleza u p\u0159\u00EDslu\u0161n\u00FDch genotyp\u016F. Byla zji\u0161t\u011Bna vysok\u00E1 prevalence mutac\u00ED C282Y a H63D u dan\u00FDch pacient\u016F, je\u017E byla doprov\u00E1zena m\u00EDrn\u00FDm stupn\u011Bm p\u0159et\u00ED\u017Een\u00ED \u017Eelezem, z\u00E1visl\u00FDm na genotypu."@cs . "The aim of the study was to determine the prevalence of mutations in the HFE and TFR2 genes together with HCV infection in patients with porphyria cutanea tarda in the Czech population, and to make comparison of the iron status among the respective genotypes. There was a very high prevalence of the C282Y and H63D mutations observed in patients with PCT accompanied by mild degrees of iron overload, which was genotype dependent." . "Dostal\u00EDkov\u00E1-\u010Cimburov\u00E1, Mark\u00E9ta" . . "3" . "Kr\u00E1tk\u00E1, Karol\u00EDna" . . . "RIV/00216208:11120/08:00000814!RIV09-MSM-11120___" . "Michal\u00EDkov\u00E1, Helena" . . "11120" . . . "RIV/00216208:11120/08:00000814" . . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . "000258470700009" . . . "High prevalence of HFE gene mutations in patients with porphyria cutanea tarda in the Czech Republic" . . . . . "0007-0963" . "Z(MSM0021620814)" . "6"^^ . "High prevalence of HFE gene mutations in patients with porphyria cutanea tarda in the Czech Republic"@en . "5"^^ . "Vr\u00E1nov\u00E1, Jana" . "High prevalence of HFE gene mutations in patients with porphyria cutanea tarda in the Czech Republic" . "British Journal of Dermatology" . . "6"^^ . . "Vysok\u00E1 prevalence mutac\u00ED v HFE genu u pacient\u016F s porphyria cutanea tarda v \u010Cesk\u00E9 republice"@cs . . . "Vysok\u00E1 prevalence mutac\u00ED v HFE genu u pacient\u016F s porphyria cutanea tarda v \u010Cesk\u00E9 republice"@cs .