"SE - \u0160v\u00E9dsk\u00E9 kr\u00E1lovstv\u00ED" . . . . "Background: Transcranial magnetic stimulation (rTMS) can modulate cortical activity. The goal of our study was to assess whether rTMS would facilitate effect of serotonin reuptake inhibitors in patients with panic disorder. Method: Fifteen patients suffering from panic disorder resistant to serotonin reuptake inhibitor (SRI) therapy were randomly assigned to either active or to sham rTMS. The aim of the study was to compare the 2 and 4 weeks efficacy of the 10 sessions 1 Hz rTMS with sham rTMS add on SRI therapy. We use 1 Hz, 30 minutes rTMS, 110% of motor threshold administered over the right dorso-lateral prefrontal cortex (DLPFC). The same time schedule was used for sham administration. Fifteen patients finished the study,. Psychopathology was assessed using the rating scales CGI, HAMA, PDSS and BAI before the treatment, immediately after the experimental treatment and 2 weeks after the experimental treatment by an independent reviewer. Results: Both groups improved during the study period but the" . "33-38" . . "1" . "Pozad\u00ED: Transcranial magnetick\u00FD stimulation (rTMS) m\u016F\u017Ee p\u0159izp\u016Fsobit kortik\u00E1ln\u00ED \u010Dinnost. The c\u00EDl na\u0161ich stud\u016F byl ten ocenit whether rTMS usnadnit \u00FA\u010Dinek serotonin reuptake tlumi\u010D nemocni\u010Dn\u00EDch pacient\u016F with panick\u00FD nepo\u0159\u00E1dek. Metody: Patn\u00E1ct pacient\u016F suffering z panick\u00E9ho nepo\u0159\u00E1dku odoln\u00E9ho proti serotonin reuptake tlumi\u010D (SRI) therapy bylo n\u00E1hodn\u011B p\u0159ev\u00E9st na jeden ze dvou \u010Dinn\u00FD nebo to p\u0159edst\u00EDrat rTMS. The zac\u00EDlen\u00ED the stud\u016F bylo to porovnat the 2 a 4 weeks \u00FA\u010Dinnost the 10 soud\u016F 1 Hz rTMS with fale\u0161n\u00FD rTMS dod\u00E1 SRI therapy. We use 1 Hz, 30 minut rTMS, 110% motoru threshold spravovalo nad the prav\u00FD dorso-postrann\u00ED t\u00FDkaj\u00EDc\u00ED se st\u0159edn\u00ED \u010D\u00E1sti kosti \u010Dichov\u00E9 k\u016Fra mozkov\u00E1 (DLPFC). The st\u00E1le stejn\u00FD time seznam u\u017E\u00EDval se pro fale\u0161nou spr\u00E1vu. Patn\u00E1ct pacient\u016F dokon\u010Den\u00E9 the study,. Psychopathology byl hodnocen using the p\u0159edpis dan\u00E9 v\u00E1hy OBECN\u00C9 ROZHRAN\u00CD BR\u00C1NY, HAMA, PDSS a BAI p\u0159ed the treatment, hned po the experiment\u00E1ln\u00ED treatment a 2 weeks po the experiment\u00E1ln\u00ED treatment u nez\u00E1visl\u00E9ho kritika. V\u00FDsledky: Oba s"@cs . "419077" . "RIV/00216208:11120/07:00000378!RIV08-MSM-11120___" . "The effect of repetitive transcranial magnetic stimulation (rTMS) add on serotonin reuptake inhibitors in patients with panic disorder: a randomized, double mind sham controlled study" . . "7"^^ . "RIV/00216208:11120/07:00000378" . . "Kope\u010Dek, Miloslav" . "Hor\u00E1\u010Dek, Ji\u0159\u00ED" . "Z\u00E1lesk\u00FD, Richard" . . "Pa\u0161kov\u00E1, Be\u00E1ta" . . . "Bare\u0161, Martin" . . . "5"^^ . . "Background: Transcranial magnetic stimulation (rTMS) can modulate cortical activity. The goal of our study was to assess whether rTMS would facilitate effect of serotonin reuptake inhibitors in patients with panic disorder. Method: Fifteen patients suffering from panic disorder resistant to serotonin reuptake inhibitor (SRI) therapy were randomly assigned to either active or to sham rTMS. The aim of the study was to compare the 2 and 4 weeks efficacy of the 10 sessions 1 Hz rTMS with sham rTMS add on SRI therapy. We use 1 Hz, 30 minutes rTMS, 110% of motor threshold administered over the right dorso-lateral prefrontal cortex (DLPFC). The same time schedule was used for sham administration. Fifteen patients finished the study,. Psychopathology was assessed using the rating scales CGI, HAMA, PDSS and BAI before the treatment, immediately after the experimental treatment and 2 weeks after the experimental treatment by an independent reviewer. Results: Both groups improved during the study period but the"@en . "Pra\u0161ko, Pavlov J\u00E1n" . . "4"^^ . "\u00DA\u010Dinek repetitivn\u00ED transkrani\u00E1ln\u00ED magnetick\u00E9 stimulace (rTMS) dod\u00E1 serotonin reuptake inhibitor\u016F u hospitalizovan\u00FDch pacient\u016F s panickou poruchou"@cs . "[F3674DA4BC90]" . "panic disorder; repetitive transcranial magnetic stimulation; rTMS; antidepressants"@en . "Nov\u00E1k, Petr" . "The effect of repetitive transcranial magnetic stimulation (rTMS) add on serotonin reuptake inhibitors in patients with panic disorder: a randomized, double mind sham controlled study"@en . . "\u00DA\u010Dinek repetitivn\u00ED transkrani\u00E1ln\u00ED magnetick\u00E9 stimulace (rTMS) dod\u00E1 serotonin reuptake inhibitor\u016F u hospitalizovan\u00FDch pacient\u016F s panickou poruchou"@cs . "The effect of repetitive transcranial magnetic stimulation (rTMS) add on serotonin reuptake inhibitors in patients with panic disorder: a randomized, double mind sham controlled study"@en . "Neuroendocrinology Letters" . . "The effect of repetitive transcranial magnetic stimulation (rTMS) add on serotonin reuptake inhibitors in patients with panic disorder: a randomized, double mind sham controlled study" . "P(1M0517), P(NF7565)" . "11120" . "0172-780X" . . . . . . "28" .