"\u010Casnou a lok\u00E1ln\u00ED atrofii medi\u00E1ln\u00ED \u010D\u00E1sti tempor\u00E1ln\u00EDch lalok\u016F u pacient\u016F s Alzheimerovou nemoc\u00ED (AN) lze na magnetick\u00E9 rezonanci m\u011B\u0159it r\u016Fzn\u00FDmi zp\u016Fsoby. Jednoduch\u00E1 a rychl\u00E1 semikvantitativn\u00ED vizu\u00E1ln\u00ED metoda hodnot\u00ED m\u00EDru atrofie mediotempor\u00E1ln\u00ED oblasti (MTA) do p\u011Bti kategori\u00ED vyj\u00E1d\u0159en\u00E9 jako sk\u00F3re MTA s rozsahem od 0 (\u017E\u00E1dn\u00E1 atrofie) do 4 (z\u0159eteln\u00E1 atrofie) podle \u0161\u00ED\u0159ky nebo v\u00FD\u0161ky vybran\u00FDch t\u0159\u00ED mediotempor\u00E1ln\u00EDch struktur. U 20 pacient\u016F s Alzheimerovou nemoc\u00ED a 25 kognitivn\u011B zdrav\u00FDch senior\u016F bylo analyzov\u00E1no sk\u00F3re MTA vpravo a vlevo a ve vztahu ke kognitivn\u00EDmu posti\u017Een\u00ED. T\u00E9m\u011B\u0159 60 % kognitivn\u011B zdrav\u00FDch senior\u016F m\u011Blo sk\u00F3re MTA ? 0,5. Naopak podobn\u00FD pod\u00EDl pacient\u016F s AN (65 %) m\u011Bl sk\u00F3re MTA ? 2. Zpr\u016Fm\u011Brn\u011Bn\u00E9 sk\u00F3re MTA z lev\u00E9 i prav\u00E9 hemisf\u00E9ry bylo u pacient\u016F s AN statisticky vy\u0161\u0161\u00ED (pr\u016Fm\u011Br 2,1) ne\u017E u zdrav\u00FDch senior\u016F (pr\u016Fm\u011Br 0,6) (p < 0.001). U pacient\u016F s AN chyb\u00ED vztah mezi velikost\u00ED mediotempor\u00E1ln\u00EDch oblast\u00ED s v\u00FDsledky kognitivn\u00EDch v\u00FDkonnosti. U zdrav\u00FDch senior\u016F souvis\u00ED zachoval\u00FD objem mediotempor\u00E1ln\u00EDch region\u016F" . . "Tint\u011Bra, J." . "Visual rating of medial temporal lobe atrophy on magnetic resonance imaging in Alzheimer\u00B4s disease"@en . "P(1M0517)" . . "Vizu\u00E1ln\u00ED kategorizace mediotempor\u00E1ln\u00ED atrofie na MR mozku u Alzheimerovy nemoci" . . "Barto\u0161, Ale\u0161" . "\u010Casnou a lok\u00E1ln\u00ED atrofii medi\u00E1ln\u00ED \u010D\u00E1sti tempor\u00E1ln\u00EDch lalok\u016F u pacient\u016F s Alzheimerovou nemoc\u00ED (AN) lze na magnetick\u00E9 rezonanci m\u011B\u0159it r\u016Fzn\u00FDmi zp\u016Fsoby. Jednoduch\u00E1 a rychl\u00E1 semikvantitativn\u00ED vizu\u00E1ln\u00ED metoda hodnot\u00ED m\u00EDru atrofie mediotempor\u00E1ln\u00ED oblasti (MTA) do p\u011Bti kategori\u00ED vyj\u00E1d\u0159en\u00E9 jako sk\u00F3re MTA s rozsahem od 0 (\u017E\u00E1dn\u00E1 atrofie) do 4 (z\u0159eteln\u00E1 atrofie) podle \u0161\u00ED\u0159ky nebo v\u00FD\u0161ky vybran\u00FDch t\u0159\u00ED mediotempor\u00E1ln\u00EDch struktur. U 20 pacient\u016F s Alzheimerovou nemoc\u00ED a 25 kognitivn\u011B zdrav\u00FDch senior\u016F bylo analyzov\u00E1no sk\u00F3re MTA vpravo a vlevo a ve vztahu ke kognitivn\u00EDmu posti\u017Een\u00ED. T\u00E9m\u011B\u0159 60 % kognitivn\u011B zdrav\u00FDch senior\u016F m\u011Blo sk\u00F3re MTA ? 0,5. Naopak podobn\u00FD pod\u00EDl pacient\u016F s AN (65 %) m\u011Bl sk\u00F3re MTA ? 2. Zpr\u016Fm\u011Brn\u011Bn\u00E9 sk\u00F3re MTA z lev\u00E9 i prav\u00E9 hemisf\u00E9ry bylo u pacient\u016F s AN statisticky vy\u0161\u0161\u00ED (pr\u016Fm\u011Br 2,1) ne\u017E u zdrav\u00FDch senior\u016F (pr\u016Fm\u011Br 0,6) (p < 0.001). U pacient\u016F s AN chyb\u00ED vztah mezi velikost\u00ED mediotempor\u00E1ln\u00EDch oblast\u00ED s v\u00FDsledky kognitivn\u00EDch v\u00FDkonnosti. U zdrav\u00FDch senior\u016F souvis\u00ED zachoval\u00FD objem mediotempor\u00E1ln\u00EDch region\u016F"@cs . . . "Suppl. 3" . . . "Vizu\u00E1ln\u00ED kategorizace mediotempor\u00E1ln\u00ED atrofie na MR mozku u Alzheimerovy nemoci"@cs . "4"^^ . "RIV/00216208:11120/07:00000315!RIV08-MSM-11120___" . "11" . . "\u0158\u00EDpov\u00E1, D." . . . "CZ - \u010Cesk\u00E1 republika" . "Alzheimer\u00B4s disease; diagnosis; magnetic resonance imaging of the brain; hippocampus; atrophy; MTA score"@en . . . "49-52" . . "11120" . . . . "Psychiatrie" . "Dibl\u00EDkov\u00E1, F." . "RIV/00216208:11120/07:00000315" . "Zach, Petr" . "[895C6DDD89BC]" . . "1211-7579" . "Visual rating of medial temporal lobe atrophy on magnetic resonance imaging in Alzheimer\u00B4s disease"@en . "6"^^ . "Brunovsk\u00FD, Martin" . . "Vizu\u00E1ln\u00ED kategorizace mediotempor\u00E1ln\u00ED atrofie na MR mozku u Alzheimerovy nemoci"@cs . . . "458087" . "Early and focal atrophy of medial temporal lobes on magnetic resonance imaging (MRI) in patients with Alzheimer\u00B4s disease (AD) can be measured in several ways. Medial temporal lobe atrophy (MTA) can be rated into five categories expressed as MTA scores ranging from 0 (no atrophy) to 4 (severe atrophy) using a simple and quick semiquantitative method according to the combined widths or the height of selected three mediotemporal structures. The MTA score was assessed in 20 patients with probable Alzheimer's disease and 25 cognitively normal seniors. Nearly 60 % cognitively normal seniors had the MTA score ? 0,5. A similar proportion of patients with AD (65 %) had the MTA score ? 2. The averaged MTA score from both hemispheres was significantly higher in AD patients (average 2,1) than in healthy seniors (average 0,6) (p <0,001). We did not find the relationship between MTA score and cognitive performance in AD patients. In controls the preserved volume of the medial temporal lobe region is relate"@en . "3"^^ . "Vizu\u00E1ln\u00ED kategorizace mediotempor\u00E1ln\u00ED atrofie na MR mozku u Alzheimerovy nemoci" .