. . "1043-4666" . "Cytokine" . "11120" . "479182" . "http://dx.doi.org/10.1016/j.cyto.2006.09.002" . "\u0160enolt, L." . . . "I, Z(MZ0RU2005)" . "6"^^ . "Housa, Daniel" . "Increased adiponectin is negatively linked to the local inflammatory process in patients with rheumatoid arthritis" . "Adiponectin has been shown to exert insulin-sensitizing, anti-atherogenic, and anti-inflammatory properties in metabolic diseases. It has been suggested that adiponectin may play a role in rheumatoid arthritis (RA). To assess adiponectin in serum and synovial fluid from patients with RA and osteoarthritis (OA), and in serum from healthy controls. Adiponectin and CRP levels were analyzed by ELISA. The clinical activity of RA patients was assessed according to the 28 joint count Disease Activity Score. Synovial fluid adiponectin was significantly higher in RA than in OA patients (p < 0.001). Adiponectin was negatively associated with the leukocyte count in RA synovial fluid (r = -0.45, p < 0.05). Serum adiponectin was higher in RA compared to healthy controls) < 0.02), however comparable to OA patients. Serum adiponectin was higher than in synovial fluid in both diseases (p < 0.001). In general, women had higher adiponectin levels than men. Adiponectin was not related to age, disease duratio"@en . "Increased adiponectin is negatively linked to the local inflammatory process in patients with rheumatoid arthritis" . "10.1016/j.cyto.2006.09.002" . . . "000243154800004" . . . . "[A49A401D5ED0]" . . "RIV/00216208:11120/06:00003043!RIV12-MSM-11120___" . . "Increased adiponectin is negatively linked to the local inflammatory process in patients with rheumatoid arthritis"@en . "5-6" . "35" . "adiponectin; rheumatoid arthritis; osteoarthritis"@en . . . "Adiponectin has been shown to exert insulin-sensitizing, anti-atherogenic, and anti-inflammatory properties in metabolic diseases. It has been suggested that adiponectin may play a role in rheumatoid arthritis (RA). To assess adiponectin in serum and synovial fluid from patients with RA and osteoarthritis (OA), and in serum from healthy controls. Adiponectin and CRP levels were analyzed by ELISA. The clinical activity of RA patients was assessed according to the 28 joint count Disease Activity Score. Synovial fluid adiponectin was significantly higher in RA than in OA patients (p < 0.001). Adiponectin was negatively associated with the leukocyte count in RA synovial fluid (r = -0.45, p < 0.05). Serum adiponectin was higher in RA compared to healthy controls) < 0.02), however comparable to OA patients. Serum adiponectin was higher than in synovial fluid in both diseases (p < 0.001). In general, women had higher adiponectin levels than men. Adiponectin was not related to age, disease duratio" . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . "RIV/00216208:11120/06:00003043" . . "1"^^ . "Increased adiponectin is negatively linked to the local inflammatory process in patients with rheumatoid arthritis"@en . . "4"^^ . .