. . "Bare\u0161, Martin" . . . . "Kraj\u010Da, V." . "Introduction: Previous studies of patients with unipolar depression have shown that depressive symptoms are caused by dysfunction of the limbic and frontal lobe regions and clinical response to treatment is associated with a reciprocal pattern of subcortical and limbic metabolic decreases and cortical increases. The aim of our study was to examine time-specific (1-week vs. baseline and 4-week vs. baseline) and response-specific (responders vs. non-responders) differences in brain electrical activities in patients with resistant depressive disorder. Method: The subjects were 25 inpatients with treatment resistant depression. EEG data and response to treatment were monitored at baseline and after 1 and 4 weeks on an antidepressant treatment. Low-resolution brain electromagnetic tomography (LORETA) was computed from spectrally analyzed EEG data, and differences between 1-week and 4-week treatment-induced changes in responders and non-responders were displayed as statistical parametric maps of voxel-by-vo" . "1211-7579" . "Zm\u011Bny EEG tomografie (LORETA) u pacient\u016F s farmakorezistentn\u00ED depres\u00ED po 1 a 4 t\u00FDdnech l\u00E9\u010Dby v z\u00E1vislosti na klinick\u00E9 odpov\u011Bdi"@cs . "[A29AC0486650]" . . "11120" . "treatment resistant depression; antidepressant therapy; EEG; low-resolution electromagnetic tomography (LORETA)"@en . "Introduction: Previous studies of patients with unipolar depression have shown that depressive symptoms are caused by dysfunction of the limbic and frontal lobe regions and clinical response to treatment is associated with a reciprocal pattern of subcortical and limbic metabolic decreases and cortical increases. The aim of our study was to examine time-specific (1-week vs. baseline and 4-week vs. baseline) and response-specific (responders vs. non-responders) differences in brain electrical activities in patients with resistant depressive disorder. Method: The subjects were 25 inpatients with treatment resistant depression. EEG data and response to treatment were monitored at baseline and after 1 and 4 weeks on an antidepressant treatment. Low-resolution brain electromagnetic tomography (LORETA) was computed from spectrally analyzed EEG data, and differences between 1-week and 4-week treatment-induced changes in responders and non-responders were displayed as statistical parametric maps of voxel-by-vo"@en . "Suppl. 3" . "\u00DAvod: P\u0159edchoz\u00ED studie u depresivn\u00EDch nemocn\u00FDch prok\u00E1zaly, \u017Ee depresivn\u00ED symptomy jsou d\u016Fsledkem dysfunkce limbick\u00FDch a front\u00E1ln\u00EDch oblast\u00ED, a pozitivn\u00ED odpov\u011B\u010F na l\u00E9\u010Dbu je doprov\u00E1zen\u00E1 recipro\u010Dn\u00EDmi zm\u011Bnami mozkov\u00E9ho metabolismu v t\u011Bchto oblastech. C\u00EDlem na\u0161\u00ED pr\u00E1ce bylo p\u0159ezkoum\u00E1n\u00ED rozd\u00EDl\u016F v distribuci mozkov\u00E9 elektrick\u00E9 aktivity nemocn\u00FDch s rezistentn\u00ED depresivn\u00ED poruchou v z\u00E1vislosti na \u010Dase (po 1 a 4 t\u00FDdnech l\u00E9\u010Dby) a odpov\u011Bdi na l\u00E9\u010Dbu. Metodika: 25 pacient\u016F s rezistentn\u00ED depresivn\u00ED poruchou bylo vy\u0161et\u0159eno klinicky a pomoc\u00ED EEG na za\u010D\u00E1tku, po 1 t\u00FDdnu a po 4 t\u00FDdnech nov\u00E9 antidepresivn\u00ED l\u00E9\u010Dby. Proudov\u00E1 hustota elektrick\u00E9 aktivity (LORETA) byla ur\u010Dena ze spektr\u00E1ln\u011B analyzovan\u00FDch EEG dat a rozd\u00EDly jednot\u00FDdenn\u00EDch a \u010Dty\u0159t\u00FDdenn\u00EDch l\u00E9\u010Debn\u00FDch efekt\u016F u respond\u00E9r\u016F a nonrespond\u00E9r\u016F byly zobrazeny v podob\u011B statistick\u00FDch parametrick\u00FDch map p\u00E1rov\u00FDch t-test\u016F. V\u00FDsledky: Po jednom t\u00FDdnu l\u00E9\u010Dby do\u0161lo u respond\u00E9r\u016F ke zv\u00FD\u0161en\u00ED excita\u010Dn\u00EDch proudov\u00FDch hustot (beta p\u00E1smo) v oblasti zadn\u00EDho cingula a insuly, zat\u00EDmco nonrespond\u00E9"@cs . . . "10" . . . "The response-specific changes in EEG tomography (LORETA) after 1 and 4 weeks of treatment in patients with drug-resistant depression"@en . . "Kope\u010Dek, Miloslav" . "CZ - \u010Cesk\u00E1 republika" . "The response-specific changes in EEG tomography (LORETA) after 1 and 4 weeks of treatment in patients with drug-resistant depression" . . . . "Brunovsk\u00FD, Martin" . "497409" . "71-79" . "The response-specific changes in EEG tomography (LORETA) after 1 and 4 weeks of treatment in patients with drug-resistant depression" . . . . "Ti\u0161lerov\u00E1, Barbora" . "7"^^ . "Stopkov\u00E1, Pavla" . . "RIV/00216208:11120/06:00000008!RIV07-MSM-11120___" . . "9"^^ . "Psychiatrie" . . "\u0160\u00F3\u0161, Petr" . "Nov\u00E1k, T." . "The response-specific changes in EEG tomography (LORETA) after 1 and 4 weeks of treatment in patients with drug-resistant depression"@en . . "Zm\u011Bny EEG tomografie (LORETA) u pacient\u016F s farmakorezistentn\u00ED depres\u00ED po 1 a 4 t\u00FDdnech l\u00E9\u010Dby v z\u00E1vislosti na klinick\u00E9 odpov\u011Bdi"@cs . . "P(1M0517)" . "Z\u00E1v\u011B\u0161ick\u00E1, Lucie" . "9"^^ . "RIV/00216208:11120/06:00000008" .