"\u010Cesko-slovensk\u00E1 pediatrie" . . "Pituitary Morphology in Patients with Combined Pituitary Hormone Deficiency Due to PROP1 Gene Mutations"@en . "Lebl, Jan" . "Pacienti s mutac\u00ED v genu PROP1 maj\u00ED kombinovan\u00FD deficit pituit\u00E1rn\u00EDch hormon\u016F (GH, TSH, prolaktin, FSH/LH a ACTH) a abnorm\u00E1ln\u00ED morfologii hypof\u00FDzy ve smyslu hypo- nebo naopak hyperplazie. Ve skupin\u011B 17 \u010Desk\u00FDch pacient\u016F sPROP1 mutac\u00ED podporuje rozlo\u017Een\u00ED n\u00E1lez\u016F podle v\u011Bku prvn\u00EDho vy\u0161et\u0159en\u00ED hypot\u00E9zu o hyperplazii hypof\u00FDzy v prvn\u00EDch letech \u017Eivota n\u00E1sledovanou spont\u00E1nn\u00ED regres\u00ED vedouc\u00ED kobrazu hypopl\u00E1zie hypof\u00FDzy a\u017E empty sella." . . . "Morfologie hypof\u00FDzy u pacient\u016F s kombinovan\u00FDm deficitem pituit\u00E1rn\u00EDch hormon\u016F na podklad\u011B mutace v PROP1 genu"@cs . "PROP1 gene mutations lead to multiple pituitary hormone deficiency including impaired secretion of growth hormone, TSH, prolactin, FSH/LH and ACTH. Abnormal pituitary morphology is an additional feature raging from pituitary hypoplasia or empty sella to pituitary hyperplasia. The distribution of findings according to age at first examination among 17 Czech patients with PROP1 mutation supports the hypothesis on pituitary hyperplasia within the first years of life, followed by a spontaneous regression leading to pituitary hypoplasia or empty sella."@en . "Z(MSM0021620814)" . "2"^^ . "11120" . . . . "Morfologie hypof\u00FDzy u pacient\u016F s kombinovan\u00FDm deficitem pituit\u00E1rn\u00EDch hormon\u016F na podklad\u011B mutace v PROP1 genu" . "11"^^ . . "Pituitary Morphology in Patients with Combined Pituitary Hormone Deficiency Due to PROP1 Gene Mutations"@en . "RIV/00216208:11120/05:00009553" . "Pacienti s mutac\u00ED v genu PROP1 maj\u00ED kombinovan\u00FD deficit pituit\u00E1rn\u00EDch hormon\u016F (GH, TSH, prolaktin, FSH/LH a ACTH) a abnorm\u00E1ln\u00ED morfologii hypof\u00FDzy ve smyslu hypo- nebo naopak hyperplazie. Ve skupin\u011B 17 \u010Desk\u00FDch pacient\u016F sPROP1 mutac\u00ED podporuje rozlo\u017Een\u00ED n\u00E1lez\u016F podle v\u011Bku prvn\u00EDho vy\u0161et\u0159en\u00ED hypot\u00E9zu o hyperplazii hypof\u00FDzy v prvn\u00EDch letech \u017Eivota n\u00E1sledovanou spont\u00E1nn\u00ED regres\u00ED vedouc\u00ED kobrazu hypopl\u00E1zie hypof\u00FDzy a\u017E empty sella."@cs . . . . "7"^^ . . "338;344" . "531213" . . . "Morfologie hypof\u00FDzy u pacient\u016F s kombinovan\u00FDm deficitem pituit\u00E1rn\u00EDch hormon\u016F na podklad\u011B mutace v PROP1 genu"@cs . "Vos\u00E1hlo, Jan" . . "60" . "RIV/00216208:11120/05:00009553!RIV06-MSM-11120___" . . "CZ - \u010Cesk\u00E1 republika" . . . "6" . "Morfologie hypof\u00FDzy u pacient\u016F s kombinovan\u00FDm deficitem pituit\u00E1rn\u00EDch hormon\u016F na podklad\u011B mutace v PROP1 genu" . . "0069-2328" . . . "[4AC272EE2824]" . "Pituitary; Morphology; Patients; Combined; Pituitary; Hormone; Deficiency; PROP1; Mutations"@en . .