"8"^^ . . "10.1099/jmm.0.45716-0" . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . "The purpose of the present study was to investigate the diversity of the genes encoding aminoglycoside-modifying enzymes and their association with class 1 integrons in three pan-European clones of Acinetobacter baumannii. The study collection included 106 multidrug-resistant strains previously allocated to clone I (n = 56), clone 11 (n = 36) and clone III (n = 6) and a heterogeneous group of other strains (n = 8), using AFLP fingerprinting and ribotyping. The strains were from hospitals of the Czech Republic (n = 70; collected 1991-2001) and 12 other European countries (n = 36; 1982-1998). Using PCR, at least one of the following aminoglycoside-resistance genes was detected in 101 (95%) strains: aphA 1 (n = 76), aacC1 (n = 68), aac(A 1 (n = 68), aphA6 (n = 55), aadB (n = 31), aacC2 (n = 7) and aacA4 (n = 3). A combination of two to five different resistance genes was observed in 89 strains (84%), with a total of 12 different combinations. PCR mapping revealed that aacC1, aadA 1 and aacA4 were each as"@en . "Diversity of aminoglycoside-resistance genes and their association with class 1 integrons among strains of pan-European Acinetobacter baumannii clones"@en . "12" . . "http://dx.doi.org/10.1099/jmm.0.45716-0" . . "0022-2615" . "The purpose of the present study was to investigate the diversity of the genes encoding aminoglycoside-modifying enzymes and their association with class 1 integrons in three pan-European clones of Acinetobacter baumannii. The study collection included 106 multidrug-resistant strains previously allocated to clone I (n = 56), clone 11 (n = 36) and clone III (n = 6) and a heterogeneous group of other strains (n = 8), using AFLP fingerprinting and ribotyping. The strains were from hospitals of the Czech Republic (n = 70; collected 1991-2001) and 12 other European countries (n = 36; 1982-1998). Using PCR, at least one of the following aminoglycoside-resistance genes was detected in 101 (95%) strains: aphA 1 (n = 76), aacC1 (n = 68), aac(A 1 (n = 68), aphA6 (n = 55), aadB (n = 31), aacC2 (n = 7) and aacA4 (n = 3). A combination of two to five different resistance genes was observed in 89 strains (84%), with a total of 12 different combinations. PCR mapping revealed that aacC1, aadA 1 and aacA4 were each as" . . . . . "Journal of Medical Microbiology" . "Diversity of aminoglycoside-resistance genes and their association with class 1 integrons among strains of pan-European Acinetobacter baumannii clones" . "5"^^ . . . "000225893300010" . . . . "53" . "Diversity of aminoglycoside-resistance genes and their association with class 1 integrons among strains of pan-European Acinetobacter baumannii clones" . "RIV/00216208:11120/04:00003836!RIV12-MSM-11120___" . . "560923" . "RIV/00216208:11120/04:00003836" . "Diversity of aminoglycoside-resistance genes and their association with class 1 integrons among strains of pan-European Acinetobacter baumannii clones"@en . . . "1"^^ . "[F050FFB037F0]" . "11120" . . "Nemec, Alexandr" . . "Antibiotic-Resistance; Identification; Hospitals; PCR; Reveals; Regions; Spain"@en . . "P(GA310/01/1540), V" . . .