"186" . "[2449FF6AA770]" . "P(GA304/00/1481), P(GA304/02/0342), P(GA311/94/0810), Z(AV0Z5039906), Z(MSM 111100003)" . "The effect of bromide on the ultrastructure of rat thyrocytes"@en . "Electron microscopic examination of thyroid tissue following administration of bromide to rats showed marked hypertrophy and hyperplasia in the thyrocytes, microfollicular rearrangement and lowered volume of colloid. The luminal surface of the thyrocytes showed increased size and number of microvilli, often filling the microlumen. Most of the nuclei were irregular in shape with unusual incisions and a higher density of chromatin. Proliferation of ER was seen with significantly dilated cisterns containing low electron density material. The Golgi complex was well developed and larger in rats receiving 10 mg Br-/l drinking water (16 days) and 100 mg Br-/l (16 and 66 days) than in control rats. Granules and small spherical structures (50-100 nm) appeared in the subapical part of the cytoplasm and their number increased in animals after administration of 50 mg Br-/l (16 and 66 days), 100 mg Br-/l (16 and 66 days), 200 and 400 mg Br-/l (133 days)."@en . "The effect of bromide on the ultrastructure of rat thyrocytes" . . "0940-9602" . "RIV/00216208:11120/04:00002997" . "http://dx.doi.org/10.1016/S0940-9602(04)80004-9" . "000222263500003" . . "6"^^ . "Electron microscopic examination of thyroid tissue following administration of bromide to rats showed marked hypertrophy and hyperplasia in the thyrocytes, microfollicular rearrangement and lowered volume of colloid. The luminal surface of the thyrocytes showed increased size and number of microvilli, often filling the microlumen. Most of the nuclei were irregular in shape with unusual incisions and a higher density of chromatin. Proliferation of ER was seen with significantly dilated cisterns containing low electron density material. The Golgi complex was well developed and larger in rats receiving 10 mg Br-/l drinking water (16 days) and 100 mg Br-/l (16 and 66 days) than in control rats. Granules and small spherical structures (50-100 nm) appeared in the subapical part of the cytoplasm and their number increased in animals after administration of 50 mg Br-/l (16 and 66 days), 100 mg Br-/l (16 and 66 days), 200 and 400 mg Br-/l (133 days)." . . . "3" . . . "The effect of bromide on the ultrastructure of rat thyrocytes" . . . "Annals of Anatomy" . . "10.1016/S0940-9602(04)80004-9" . "561807" . "RIV/00216208:11120/04:00002997!RIV12-GA0-11120___" . "11120" . . . . . "Titlbach, Milan" . "DE - Spolkov\u00E1 republika N\u011Bmecko" . . . . "8"^^ . . "The effect of bromide on the ultrastructure of rat thyrocytes"@en . . "thyroid gland; thyrocytes; rat; bromide"@en . "1"^^ . . . "Velick\u00FD, Jan" . .