"RIV/00216208:11120/04:00001133" . . "DE - Spolkov\u00E1 republika N\u011Bmecko" . . . "159" . "11120" . "Reinnervation;musculocutaneous;nerve;stump;after;direct;reconnection;spinal;segment;nerve;graft;following;avulsion;ventral;spinal;roots;comparison;intrathecal;administration;brain-derived;neurotrophic"@en . . . "Reinnervation of the rat musculocutaneous nerve stump after its direct reconnection with the C5 spinal cord segment by the nerve graft following avulsion of the ventral spinal roots"@en . "Reinervace pah\u00FDlu krys\u00EDho nervus musculocutaneus po jeho p\u0159\u00EDm\u00E9m znovuspojen\u00ED na m\u00ED\u0161n\u00ED segment C5 nervov\u00FDm \u0161t\u011Bpem n\u00E1sledkem avulze ventr\u00E1ln\u00ED m\u00ED\u0161n\u00EDch ko\u0159en\u016F"@cs . "425;432" . . . "Reinervace pah\u00FDlu krys\u00EDho nervus musculocutaneus po jeho p\u0159\u00EDm\u00E9m znovuspojen\u00ED na m\u00ED\u0161n\u00ED segment C5 nervov\u00FDm \u0161t\u011Bpem n\u00E1sledkem avulze ventr\u00E1ln\u00ED m\u00ED\u0161n\u00EDch ko\u0159en\u016F"@cs . "Haninec, Pavel" . . "Reinnervation of the rat musculocutaneous nerve stump after its direct reconnection with the C5 spinal cord segment by the nerve graft following avulsion of the ventral spinal roots" . . "3"^^ . "Reinnervation of the rat musculocutaneous nerve stump after its direct reconnection with the C5 spinal cord segment by the nerve graft following avulsion of the ventral spinal roots"@en . . "Experimental model based on the C5 ventral root avulsion was used to evaluate the efficacy of brain-derived neurotrophic factor (BDNF) and Cerebrolysin treatment on motor neuron maintenance and survival resulted in the functional reinnervation of the nerve stump. In contrast to vehicle, BDNF treatment reduced the loss and atrophy of motor neurons and enhanced the regrowth axon sprouts into the distal stump of musculocutaneous nerve. However, the axon diameter of the myelinated fibers was smaller than those of control rats. The morphometric results were related to a low score in behavioral test similar to vehicle-treated rats. Cerebrolysin treatment greatly protected the motor neurons against cell death. Moreover, morphometric features of myelinated axons were better than those of rats treated with vehicle or BDNF. The mean score of grooming test suggested better results of the functional motor reinnervation than after BDNF administration."@en . . "584121" . . "Reinnervation of the rat musculocutaneous nerve stump after its direct reconnection with the C5 spinal cord segment by the nerve graft following avulsion of the ventral spinal roots" . "P(NF6658)" . . "[231E7E8ABC1F]" . . . "\u0160\u00E1mal, Filip" . . "RIV/00216208:11120/04:00001133!RIV/2005/MZ0/111205/N" . "0014-4819" . "5"^^ . . "Experimental Brain Research" . . "8"^^ . . . . . . . . . . . . "Experimental model based on the C5 ventral root avulsion was used to evaluate the efficacy of brain-derived neurotrophic factor (BDNF) and Cerebrolysin treatment on motor neuron maintenance and survival resulted in the functional reinnervation of the nerve stump. In contrast to vehicle, BDNF treatment reduced the loss and atrophy of motor neurons and enhanced the regrowth axon sprouts into the distal stump of musculocutaneous nerve. However, the axon diameter of the myelinated fibers was smaller than those of control rats. The morphometric results were related to a low score in behavioral test similar to vehicle-treated rats. Cerebrolysin treatment greatly protected the motor neurons against cell death. Moreover, morphometric features of myelinated axons were better than those of rats treated with vehicle or BDNF. The mean score of grooming test suggested better results of the functional motor reinnervation than after BDNF administration." . "Pr\u00E1ce popisuje reinervaci pah\u00FDlu krys\u00EDho nervus musculocutaneus po jeho p\u0159\u00EDm\u00E9m znovuspojen\u00ED na m\u00ED\u0161n\u00ED segment C5 nervov\u00FDm \u0161t\u011Bpem n\u00E1sledkem avulze ventr\u00E1ln\u00ED m\u00ED\u0161n\u00EDch ko\u0159en\u016F: srovn\u00E1n\u00ED intratek\u00E1ln\u00EDho pod\u00E1n\u00ED mozkov\u011B derivovan\u00E9ho neurotrofick\u00E9ho faktoru a Cerebrosylinu"@cs . "Hou\u0161\u0165ava, Ladislav" . "4" . . . . .