. . "V pr\u016Fb\u011Bhu prospektivn\u00ED observa\u010Dn\u00ED studie (30 dosp\u011Bl\u00FDch s ARDS l\u00E9\u010Den\u00FDch vysokofrekven\u010Dn\u00ED oscila\u010Dn\u00ED ventilac\u00ED) byla HFOV \u00FAsp\u011B\u0161n\u011B u\u017Eita u dvou d\u011Btsk\u00FDch pacient\u016F ve v\u011Bku 13 m\u011Bs\u00EDc\u016F a 17 let st\u011B\u017Ekou formou ARDS (oxygena\u010Dn\u00ED index OI=75 a 50). V obou p\u0159\u00EDpadech byl inici\u00E1ln\u011B pou\u017Eit efektivn\u00ED kontinu\u00E1ln\u00ED distenzn\u00ED tlak CDP=4,0 a 4,5 kPa, tedy vy\u0161\u0161\u00ED ne\u017E ve skupin\u011B dosp\u011Bl\u00FDch. Za veden\u00ED HFOV vedlo ji\u017E inici\u00E1ln\u011B v obou p\u0159\u00EDpadech ke zlep\u0161en\u00ED oxygena\u010Dn\u00EDch hemodynamick\u00FDch parametr\u016F ve srovn\u00E1n\u00ED se situac\u00ED p\u0159i ventilaci konven\u010Dn\u00ED. K dosa\u017Een\u00ED dobr\u00FDch oxygena\u010Dn\u00EDch parametr\u016F p\u0159i inspira\u010Dn\u00ED frakci kysl\u00EDku F1O2=0,4 do\u0161lo do 24 hodin, v jednom p\u0159\u00EDpad\u011B p\u0159i pou\u017Eit\u00ED HFOV v poloze na b\u0159i\u0161e pot\u00E9, co tento postup selhal v podm\u00EDnk\u00E1ch ventilace konven\u010Dn\u00ED. Pr\u00E1v\u011B paraleln\u00ED u\u017Eit\u00ED HFOV spolohov\u00E1n\u00EDm na b\u0159icho a z\u00E1da doporu\u010Duj\u00ED auto\u0159i testovat vdal\u0161\u00EDch klinick\u00FDch studi\u00EDch." . . "0"^^ . . . . "0"^^ . "Vyhn\u00E1nek, Franti\u0161ek" . "58" . . "492;496" . . . "0069-2328" . "5"^^ . . "Pachl, Jan" . . . . "Kripner, Ji\u0159\u00ED" . "\u00DAsp\u011Bsn\u00E1 aplikace vysokofrekven\u010Dn\u00ED oscila\u010Dn\u00ED ventilace u extr\u00E9mn\u011B z\u00E1va\u017En\u00FDch forem ARDS u d\u011Bt\u00ED"@cs . . "CZ - \u010Cesk\u00E1 republika" . . "\u00DAsp\u011Bsn\u00E1 aplikace vysokofrekven\u010Dn\u00ED oscila\u010Dn\u00ED ventilace u extr\u00E9mn\u011B z\u00E1va\u017En\u00FDch forem ARDS u d\u011Bt\u00ED"@cs . "632446" . . "[4B8E72199B52]" . . "P(GA305/00/0651), Z(MSM 111200003)" . "successful;application;high-frequency;oscillation;ventilation;extremely;severe;forms;children"@en . . . "RIV/00216208:11120/03:00007207!RIV/2004/MSM/111204/N" . "\u00DAsp\u011Bsn\u00E1 aplikace vysokofrekven\u010Dn\u00ED oscila\u010Dn\u00ED ventilace u extr\u00E9mn\u011B z\u00E1va\u017En\u00FDch forem ARDS u d\u011Bt\u00ED" . "11120" . "During the prospective observational clinical study of HFOV in adult ARDS (n=30), two children (13 months a 17 years of age) suffering from severe ARDS (oxygenation index OI=75 and 50, respectively) underwent the same therapeutical protocol. In the both cases the higher initial effective continuous distension pressure (CDP=4.0 and 4.5 kPa) was used compared with the highest CDP valuess in adult group. HFOV with such high CDP values led to improvement of oxygenation and circulatory parameters contrary to CMV period. Acceptable oxygenation parameters with the use of fraction of inspired oxygen fraction F1O2=0.4 were achieved within 24 hours period, in one case also in combination with prone/supine positioning. The authors recommend to focus next clinical trials to combined HFOV/prone supine\u201D therapeutical approach."@en . "\u00DAsp\u011Bsn\u00E1 aplikace vysokofrekven\u010Dn\u00ED oscila\u010Dn\u00ED ventilace u extr\u00E9mn\u011B z\u00E1va\u017En\u00FDch forem ARDS u d\u011Bt\u00ED" . . "11"^^ . "8" . . . "\u010Cesko-slovensk\u00E1 pediatrie" . "Bro\u017E, Ludom\u00EDr" . "Bakal\u00E1\u0159, Bohumil" . "RIV/00216208:11120/03:00007207" . . "Jandov\u00E1, Jaroslava" . "A successful application of high-frequency oscillation ventilation in extremely severe forms of ARDS in children"@en . . "6"^^ . . . . "A successful application of high-frequency oscillation ventilation in extremely severe forms of ARDS in children"@en . .