"RIV/00216208:11120/00:00003729" . "Ra\u0161ka, Ivan" . "Expression of beta-catenins and cadherins by follicular dendritic cells in human lymph nodes" . "RIV/00216208:11120/00:00003729!RIV12-MSM-11120___" . "Djaborkhel, Rashed A." . "Expression of beta-catenins and cadherins by follicular dendritic cells in human lymph nodes" . . "000165865000001" . . . . "P(VS96129)" . . . "M\u00FCller, Julius" . . "0065-1281" . . . "8"^^ . "Dvo\u0159\u00E1k, Richard" . "Mandys, V\u00E1clav" . "710991" . "follicular dendritic cells; adherens junctions; cadherins; beta-catenin; human; lymphatic follicle"@en . . . "n lymph nodes, dendritic cells form a complex meshwork and are linked by intercellular junctions. Intercellular junctions contribute to the integrity of lymphatic follicles and can potentially be affected by malignant processes in neighbouring B cells. We examined whether transmembrane molecules that constitute %22adherens junctions%22 are present in follicular dendritic cells of normal human lymph nodes. We found that follicular dendritic cells but not interdigitating dendritic cells or sinus lining cells expressed cadherin molecules. Follicular dendritic cells also expressed beta -catenin but not vinculin. The cadherin molecules, which were identified in situ with the use of a monoclonal pan-cadherin antibody, were not recognized by antibodies to E-cadherin, N-cadherin or beta -cadherin. Intrafollicularly, cadherins were clearly colocalized with beta -catenins, in a dot-like fashion. We also detected intrafollicular expression of desmogleins and desmosomal plaque proteins. These findings indic"@en . "10.1078/0065-1281-00573" . "Expression of beta-catenins and cadherins by follicular dendritic cells in human lymph nodes"@en . "102" . "16"^^ . . . "DE - Spolkov\u00E1 republika N\u011Bmecko" . "http://dx.doi.org/10.1078/0065-1281-00573" . "n lymph nodes, dendritic cells form a complex meshwork and are linked by intercellular junctions. Intercellular junctions contribute to the integrity of lymphatic follicles and can potentially be affected by malignant processes in neighbouring B cells. We examined whether transmembrane molecules that constitute %22adherens junctions%22 are present in follicular dendritic cells of normal human lymph nodes. We found that follicular dendritic cells but not interdigitating dendritic cells or sinus lining cells expressed cadherin molecules. Follicular dendritic cells also expressed beta -catenin but not vinculin. The cadherin molecules, which were identified in situ with the use of a monoclonal pan-cadherin antibody, were not recognized by antibodies to E-cadherin, N-cadherin or beta -cadherin. Intrafollicularly, cadherins were clearly colocalized with beta -catenins, in a dot-like fashion. We also detected intrafollicular expression of desmogleins and desmosomal plaque proteins. These findings indic" . "3"^^ . "Acta Histochemica" . . . "Lojda, Zden\u011Bk" . . . . "Tvrd\u00EDk, Daniel" . . "11120" . "Expression of beta-catenins and cadherins by follicular dendritic cells in human lymph nodes"@en . . "Bedn\u00E1\u0159, Blahoslav" . "[B7AC95C1CA8F]" . "4" .