"WHO Grade II Ependymomas of the Fourth Ventricle in Adults - Single Institution Experience"@en . "3"^^ . "3"^^ . "WHO Grade II ependymomy IV. komory u dosp\u011Bl\u00FDch - zku\u0161enosti s l\u00E9\u010Dbou" . "WHO Grade II Ependymomas of the Fourth Ventricle in Adults - Single Institution Experience"@en . . . . "Brad\u00E1\u010D, Ond\u0159ej" . "http://www.csnn.eu/ceska-slovenska-neurologie-clanek/who-grade-ii-ependymomy-iv-komory-u-dospelych-zkusenosti-s-lecbou-50250" . "6" . . . . . "11110" . "I, P(NT12254)" . . "\u0160tekl\u00E1\u010Dov\u00E1, Anna" . "CZ - \u010Cesk\u00E1 republika" . . "1210-7859" . "radiotherapy; survival recurrence; posterior fossa surgery; fourth ventricle; adult; ependymoma"@en . . "RIV/00216208:11110/14:10286112!RIV15-MSM-11110___" . . "000346229200012" . . . "7"^^ . . "\u010Cesk\u00E1 a slovensk\u00E1 neurologie a neurochirurgie" . . . "Bene\u0161, Vladim\u00EDr" . "\u00DAvod: Kompletn\u00ED resekce je obecn\u011B uzn\u00E1van\u00FD standard l\u00E9\u010Dby GII ependymom\u016F IV. komory u dosp\u011Bl\u00FDch, zat\u00EDmco role adjuvantn\u00ED radioterapie z\u016Fst\u00E1v\u00E1 nejist\u00E1. \u00DA\u010Delem p\u0159edkl\u00E1dan\u00E9 studie je zhodnotit lok\u00E1ln\u00ED kontrolu onemocn\u011Bn\u00ED a klinick\u00FD stav pacient\u016F s t\u00EDmto onemocn\u011Bn\u00EDm po chirurgick\u00E9 terapii. Materi\u00E1l a metody: Retrospektivn\u011B jsme zhodnotili 15 pacient\u016F (sedm mu\u017E\u016F a osm \u017Een) s histologicky verifikovan\u00FDm GII ependymomem IV. komory v \u010Dasov\u00E9m obdob\u00ED leden 2001-prosinec 2011. V\u00FDsledky: Kompletn\u00ED resekce tumoru byla dosa\u017Eena u 12 pacient\u016F, u \u017E\u00E1dn\u00E9ho z nich nebyla indikov\u00E1na adjuvantn\u00ED radioterapie. Medi\u00E1n dal\u0161\u00EDho sledov\u00E1n\u00ED byl 51 m\u011Bs\u00EDc\u016F (min.-max.; 11-123 m\u011Bs\u00EDc\u016F). Ke grafick\u00E9 recidiv\u011B do\u0161lo u jednoho pacienta, ten byl reoperov\u00E1n s \u010Dasov\u00FDm odstupem 51 m\u011Bs\u00EDc\u016F od prvn\u00EDho z\u00E1kroku. Nov\u00FD neurologick\u00FD deficit po operaci byl zaznamen\u00E1n ve dvou p\u0159\u00EDpadech. U dvou ze t\u0159\u00ED pacient\u016F po subtot\u00E1ln\u00ED resekci do\u0161lo ke grafick\u00E9 progresi rezidua po 11 a 16 m\u011Bs\u00EDc\u00EDch od prvn\u00ED operace, jeden z nich byl reoperov\u00E1n s odstupem 27 m\u011Bs\u00EDc\u016F. Adjuvantn\u00ED radioterapie byla indikov\u00E1na u obou pacient\u016F po reoperaci. Z\u00E1v\u011Br: Dle na\u0161ich dat je kompletn\u00ED resekce efektivn\u00ED a bezpe\u010Dn\u00E1 l\u00E9\u010Dba GII ependymom\u016F IV. komory u dosp\u011Bl\u00FDch. N\u00E1sledn\u00E1 radioterapie by m\u011Bla b\u00FDt rezervov\u00E1na pro p\u0159\u00EDpady subtot\u00E1ln\u00ED resekce s n\u00E1slednou progres\u00ED rezidua tumoru a reoperace." . . "Introduction: Surgical resection is a generally accepted standard treatment modality in Gll posterior fossa ependymomas in adults, while the role of adjuvant radiotherapy remains unclear. The purpose of this study was to evaluate local control of tumor growth and clinical outcome of patients after surgical treatment of Gll fourth ventricle ependymomas. Material and methods: We conducted a retrospective study of 15 adult patients (seven males and eight females) with histologically confirmed Gll fourth ventricular ependymoma between January 2001 and December 2011. Results: Gross total resection was achieved in 12 patients, none of them received adjuvant treatment after the initial surgery. Median follow-up after GTR was 51 months (min. -max.; 11-123 months). One patient showed radiographic signs of tumor recurrence and was re-operated 51 months after the initial surgery. Remaining patients were without any signs of tumor recurrence. After the surgery, a new neurological deficit occurred in two patients. Two of the three patients after subtotal tumor resection showed residual mass progression after 11 and 16 months postoperatively, one of them was re-operated 27 months after the initial surgery. Adjuvant radiotherapy was indicated in both re-operated patients. Conclusion: According to our data, gross total resection is effective and safe treatment of Gll fourth ventricle ependymomas. Adjuvant radiotherapy should be reserved for the cases where complete removal of tumor mass is not possible and residual tumor is growing, or after repeated resection."@en . "56178" . "WHO Grade II ependymomy IV. komory u dosp\u011Bl\u00FDch - zku\u0161enosti s l\u00E9\u010Dbou" . "77" . . . "WHO Grade II ependymomy IV. komory u dosp\u011Bl\u00FDch - zku\u0161enosti s l\u00E9\u010Dbou"@cs . . "[508BBAF1B237]" . "\u00DAvod: Kompletn\u00ED resekce je obecn\u011B uzn\u00E1van\u00FD standard l\u00E9\u010Dby GII ependymom\u016F IV. komory u dosp\u011Bl\u00FDch, zat\u00EDmco role adjuvantn\u00ED radioterapie z\u016Fst\u00E1v\u00E1 nejist\u00E1. \u00DA\u010Delem p\u0159edkl\u00E1dan\u00E9 studie je zhodnotit lok\u00E1ln\u00ED kontrolu onemocn\u011Bn\u00ED a klinick\u00FD stav pacient\u016F s t\u00EDmto onemocn\u011Bn\u00EDm po chirurgick\u00E9 terapii. Materi\u00E1l a metody: Retrospektivn\u011B jsme zhodnotili 15 pacient\u016F (sedm mu\u017E\u016F a osm \u017Een) s histologicky verifikovan\u00FDm GII ependymomem IV. komory v \u010Dasov\u00E9m obdob\u00ED leden 2001-prosinec 2011. V\u00FDsledky: Kompletn\u00ED resekce tumoru byla dosa\u017Eena u 12 pacient\u016F, u \u017E\u00E1dn\u00E9ho z nich nebyla indikov\u00E1na adjuvantn\u00ED radioterapie. Medi\u00E1n dal\u0161\u00EDho sledov\u00E1n\u00ED byl 51 m\u011Bs\u00EDc\u016F (min.-max.; 11-123 m\u011Bs\u00EDc\u016F). Ke grafick\u00E9 recidiv\u011B do\u0161lo u jednoho pacienta, ten byl reoperov\u00E1n s \u010Dasov\u00FDm odstupem 51 m\u011Bs\u00EDc\u016F od prvn\u00EDho z\u00E1kroku. Nov\u00FD neurologick\u00FD deficit po operaci byl zaznamen\u00E1n ve dvou p\u0159\u00EDpadech. U dvou ze t\u0159\u00ED pacient\u016F po subtot\u00E1ln\u00ED resekci do\u0161lo ke grafick\u00E9 progresi rezidua po 11 a 16 m\u011Bs\u00EDc\u00EDch od prvn\u00ED operace, jeden z nich byl reoperov\u00E1n s odstupem 27 m\u011Bs\u00EDc\u016F. Adjuvantn\u00ED radioterapie byla indikov\u00E1na u obou pacient\u016F po reoperaci. Z\u00E1v\u011Br: Dle na\u0161ich dat je kompletn\u00ED resekce efektivn\u00ED a bezpe\u010Dn\u00E1 l\u00E9\u010Dba GII ependymom\u016F IV. komory u dosp\u011Bl\u00FDch. N\u00E1sledn\u00E1 radioterapie by m\u011Bla b\u00FDt rezervov\u00E1na pro p\u0159\u00EDpady subtot\u00E1ln\u00ED resekce s n\u00E1slednou progres\u00ED rezidua tumoru a reoperace."@cs . "WHO Grade II ependymomy IV. komory u dosp\u011Bl\u00FDch - zku\u0161enosti s l\u00E9\u010Dbou"@cs . "RIV/00216208:11110/14:10286112" . .