. "16" . "Antifosfolipidov\u00FD syndrom - diagnostika, manifestace a l\u00E9\u010Dba"@cs . "Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by various potentially serious and life- threatening manifestation. APS occurs in a primary form with no associated conditions or in secondary form associated with various other ilnesses (autoimmune, neoplastic and others). APS is diagnosed according to clinically and laboratory criteris. It is characterized by recurrent arterila or venous thrombosis and/or pregnancy related complications and laboratory findings of antiphospholipid antibodies in a minimum time interval of 12 weeks between individual laboratory tests. Clinical manifestation of APS can vary and a multidisciplinary approach is needed. Catastrophic APS is very serious and life threatening condition with high mortality and morbidity, althoug read. An early diagnosis with proper therapy has a serious impact on the prognosis of patiens with APS:"@en . "Antifosfolipidov\u00FD syndrom - diagnostika, manifestace a l\u00E9\u010Dba"@cs . . . "Antifosfolipidov\u00FD syndrom - diagnostika, manifestace a l\u00E9\u010Dba" . . "1"^^ . "[C60F635AA7BB]" . "V" . "Antiphospholipid syndrome - diagnostics, maniferstation and treatment"@en . "2336-288X" . "CZ - \u010Cesk\u00E1 republika" . "1"^^ . "5" . . . "Antiphospholipid syndrome - diagnostics, maniferstation and treatment"@en . "Randomizovan\u00E1, kontrolovan\u00E1 studie ve dvou f\u00E1z\u00EDch. V prvn\u00ED otev\u0159en\u00E9 f\u00E1zi byli v\u0161echni pacienti l\u00E9\u010Deni plnou d\u00E1vkou adalimumabu. P\u0159i dosa\u017Een\u00ED stavu n\u00EDzk\u00E9 aktivity byli randomizov\u00E1ni do skupiny, kter\u00E1 pokra\u010Dovala v l\u00E9\u010Db\u011B a do skupiny, u kter\u00E9 byl biologick\u00FD l\u00E9k vysazen"@cs . . "Cifersk\u00E1, Hana" . . "11110" . . "4"^^ . "Randomizovan\u00E1, kontrolovan\u00E1 studie ve dvou f\u00E1z\u00EDch. V prvn\u00ED otev\u0159en\u00E9 f\u00E1zi byli v\u0161echni pacienti l\u00E9\u010Deni plnou d\u00E1vkou adalimumabu. P\u0159i dosa\u017Een\u00ED stavu n\u00EDzk\u00E9 aktivity byli randomizov\u00E1ni do skupiny, kter\u00E1 pokra\u010Dovala v l\u00E9\u010Db\u011B a do skupiny, u kter\u00E9 byl biologick\u00FD l\u00E9k vysazen" . . "RIV/00216208:11110/14:10283503!RIV15-MSM-11110___" . "RIV/00216208:11110/14:10283503" . . . "3412" . "Antifosfolipidov\u00FD syndrom - diagnostika, manifestace a l\u00E9\u010Dba" . "http://www.prolekare.cz/linkout/50153" . "Kardiologick\u00E1 revue - Intern\u00ED medic\u00EDna" . "systemic lupus erythematosus; antiphopholipid syndrome"@en . .