. "5"^^ . . "Multiple sclerosis (MS) has a significant impact on health-related quality of life (HRQoL) with symptoms adversely affecting many aspects of everyday living. BG-12 (dimethyl fumarate) demonstrated significant efficacy in the phase III studies DEFINE and CONFIRM in patients with relapsing-remitting MS. In CONFIRM, HRQoL was worse in patients with greater disability at baseline, and who relapsed during the study, and improved with BG-12 treatment. Mean Short Form-36 Physical Component Summary scores for BG-12 increased over 2 years and scores for placebo decreased. Coupled with clinical and neuroradiological benefits, these HRQoL results further support BG-12 as an effective oral treatment for relapsing MS." . . "Multiple sclerosis (MS) has a significant impact on health-related quality of life (HRQoL) with symptoms adversely affecting many aspects of everyday living. BG-12 (dimethyl fumarate) demonstrated significant efficacy in the phase III studies DEFINE and CONFIRM in patients with relapsing-remitting MS. In CONFIRM, HRQoL was worse in patients with greater disability at baseline, and who relapsed during the study, and improved with BG-12 treatment. Mean Short Form-36 Physical Component Summary scores for BG-12 increased over 2 years and scores for placebo decreased. Coupled with clinical and neuroradiological benefits, these HRQoL results further support BG-12 as an effective oral treatment for relapsing MS."@en . . "Zhang, Annie" . "1"^^ . . "Sheikh, Sarah I." . "Havrdov\u00E1, Eva" . "Hutchinson, Michael" . "Effects of BG-12 (dimethyl fumarate) on health-related quality of life in patients with relapsing-remitting multiple sclerosis: findings from the CONFIRM study"@en . "000331226600019" . "Effects of BG-12 (dimethyl fumarate) on health-related quality of life in patients with relapsing-remitting multiple sclerosis: findings from the CONFIRM study"@en . "2" . . . . "Phillips, J. Theodore" . "Kong, Jessica" . "20" . . . "randomized controlled trial; glatiramer acetate; quality of life; dimethyl fumarate; BG-12; relapsing-remitting; Multiple sclerosis"@en . "Effects of BG-12 (dimethyl fumarate) on health-related quality of life in patients with relapsing-remitting multiple sclerosis: findings from the CONFIRM study" . "RIV/00216208:11110/14:10218645!RIV15-MSM-11110___" . . "I, Z(MSM0021620849)" . "Fox, Robert J." . "Multiple Sclerosis" . . "Viglietta, Vissia" . "RIV/00216208:11110/14:10218645" . "10.1177/1352458513507818" . "Seidman, Emily" . "[588B403D536C]" . . . "11110" . "13"^^ . . "Sarda, Sujata P." . "13689" . "Dawson, Katherine T." . "Effects of BG-12 (dimethyl fumarate) on health-related quality of life in patients with relapsing-remitting multiple sclerosis: findings from the CONFIRM study" . "1352-4585" . "Agarwal, Sonalee" . "http://dx.doi.org/10.1177/1352458513507818" . . . . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . "Kita, Mariko" . . .