. . "RIV/00216208:11110/12:12639!RIV13-MSM-11110___" . . "systemic sclerosis; fibrosis; hedgehog signaling"@en . "Palumbo, Katrin" . "8" . "Zerr, Pawel" . . . "We demonstrated that the hedgehog pathway is activated in patients with SSc. Hedgehog signaling potently stimulates the release of collagen and myofibroblast differentiation in vitro and is sufficient to induce fibrosis in vivo. These findings identify the hedgehog cascade as a profibrotic pathway in SSc."@en . "Tom\u010D\u00EDk, Michal" . "Cordazzo, Cinzia" . "64" . . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . . . . "RIV/00216208:11110/12:12639" . "0004-3591" . . "Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis" . "http://onlinelibrary.wiley.com/doi/10.1002/art.34444/abstract;jsessionid=DF320B203BD50E01634E07F9FA6D183A.d03t02" . "Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis"@en . . "[11C7544F5D1E]" . "Arthritis & Rheumatism" . . "Horn, Angelika" . "I" . "138767" . . "Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis" . "10"^^ . "1"^^ . "Zwerina, Jochen" . . "11110" . . "We demonstrated that the hedgehog pathway is activated in patients with SSc. Hedgehog signaling potently stimulates the release of collagen and myofibroblast differentiation in vitro and is sufficient to induce fibrosis in vivo. These findings identify the hedgehog cascade as a profibrotic pathway in SSc." . "Dees, Clara" . "000306906500033" . "16"^^ . "Akhmetshina, Alfiya" . "Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis"@en . "Gusinde, Johannes" . "Avouac, Jerome" .