"49" . "Hsp90; folding; genetic variation"@en . "Phenotypic robustness is enabled by several mechanisms masking detrimental genetic variations in individuals. These mechanisms involve gene duplication and functional redundancy of cellular pathways. Recently the role of Hsp90 chaperone system was suggested in the process of buffering genetic variation on the protein level. This activity of chaperones has a profound effect on the accumulation of large numbers of phenotypically silent genotypes and thus may play an important role in evolution." . . . "Vojt\u011B\u0161ek, Bo\u0159ivoj" . "Phenotypic robustness is enabled by several mechanisms masking detrimental genetic variations in individuals. These mechanisms involve gene duplication and functional redundancy of cellular pathways. Recently the role of Hsp90 chaperone system was suggested in the process of buffering genetic variation on the protein level. This activity of chaperones has a profound effect on the accumulation of large numbers of phenotypically silent genotypes and thus may play an important role in evolution."@en . . "RIV/00209805:_____/13:#0000447" . "Folia Mendeliana" . . "Chaperones and evolution" . . "3"^^ . "CZ - \u010Cesk\u00E1 republika" . . "Chaperones and evolution"@en . "3"^^ . . . "64999" . . "RIV/00209805:_____/13:#0000447!RIV14-MZ0-00209805" . . . "0085-0748" . . "Tr\u010Dka, Filip" . . . "Chaperones and evolution" . . "[0FE17BB5F6DC]" . . "I, P(ED2.1.00/03.0101)" . "Chaperones and evolution"@en . . . "M\u00FCller, Petr" . "4"^^ . . "2" . "http://www.mzm.cz/fileadmin/user_upload/publikace/casopisy/fm_49_2_2013/fm-2-2013-abstract-10.pdf" .