. . "Navr\u00E1tilov\u00E1, Marie" . . . "Kal\u00E1bov\u00E1, Renata" . . . "Genetic testing and prevention of hereditary cancer at the MMCI \u2013 over 10 years of experience"@en . "0862-495X" . "Genetic testing and prevention of hereditary cancer at the MMCI \u2013 over 10 years of experience" . . "Bol\u010D\u00E1k, Karol" . . "Foretov\u00E1, Lenka" . . "12"^^ . . . "14"^^ . "6" . . "Va\u0161\u00ED\u010Dkov\u00E1, Petra" . "Krej\u010D\u00ED, Eva" . . . "Hereditary cancer syndromes are frequently seen in young cancer patients and patients with a positive family history. Genetic testing is important for the identifi cation of high-risk individuals, and for the early introduction of specialized preventive care or prophylactic surgeries. High-risk tumour suppressor genes (BRCA1 and BRCA2) and DNA repair genes (MLH1, MSH2 and MSH6) are responsible for a substantial part of hereditary breast, ovarian and colorectal cancer. Other hereditary cancers are seen less frequently, but genetic testing has increased for many other site-specifi c cancers and complex syndromes."@en . "hereditary cancer, syndromes, genetic testing, prevention"@en . . "3"^^ . "Schneiderov\u00E1, Monika" . . . "260415" . . "CZ - \u010Cesk\u00E1 republika" . . "Mach\u00E1\u010Dkov\u00E1, Eva" . . . . . . "Klinick\u00E1 onkologie" . . "P(NS10357), P(NS10536), Z(MZ0MOU2005)" . . . "Pal\u00E1cov\u00E1, Mark\u00E9ta" . "[DCFBD2F8B4CD]" . . "RIV/00209805:_____/10:#0000135" . "23" . "Hereditary cancer syndromes are frequently seen in young cancer patients and patients with a positive family history. Genetic testing is important for the identifi cation of high-risk individuals, and for the early introduction of specialized preventive care or prophylactic surgeries. High-risk tumour suppressor genes (BRCA1 and BRCA2) and DNA repair genes (MLH1, MSH2 and MSH6) are responsible for a substantial part of hereditary breast, ovarian and colorectal cancer. Other hereditary cancers are seen less frequently, but genetic testing has increased for many other site-specifi c cancers and complex syndromes." . "Genetic testing and prevention of hereditary cancer at the MMCI \u2013 over 10 years of experience" . "Petr\u00E1kov\u00E1, Katar\u00EDna" . . "Genetic testing and prevention of hereditary cancer at the MMCI \u2013 over 10 years of experience"@en . "Svoboda, Marek" . . "H\u00E1zov\u00E1, Jana" . "RIV/00209805:_____/10:#0000135!RIV11-MZ0-00209805" .