. . "STAT 1 levels and inducibility of its activated phosphoforms were detected by Western analysis using specific polyclonal and monoclonal antibodies. The study demonstrates STAT 1 functional abnormalities in melanoma cells. On the basis of detail analyses of patient melanoma cells with respect to the inducibility of STAT 1 phosphorylation by IFNs, four categories of patients could be distinguished: a) activation on both S 727 and Y 701, b) not inducible response, c) activation on Y 701 but not on S 727, d) heterogeneous response."@en . . . "6"^^ . "GR - \u0158eck\u00E1 republika" . . "3" . "[EF46749A0317]" . "Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation" . "6"^^ . . "6"^^ . "RIV/00209805:_____/03:00008216" . . "12" . "614186" . "P(GA301/00/0564), P(NC7139)" . "International journal of molecular medicine" . "STAT 1;malignant melanoma;signal transduction;interferons"@en . "Kova\u0159\u00EDk, Jan" . "335; 340" . . . "STAT 1 levels and inducibility of its activated phosphoforms were detected by Western analysis using specific polyclonal and monoclonal antibodies. The study demonstrates STAT 1 functional abnormalities in melanoma cells. On the basis of detail analyses of patient melanoma cells with respect to the inducibility of STAT 1 phosphorylation by IFNs, four categories of patients could be distinguished: a) activation on both S 727 and Y 701, b) not inducible response, c) activation on Y 701 but not on S 727, d) heterogeneous response." . . "Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation" . . "Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation"@en . "1107-3756" . . "Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation"@en . . . . . . . "Boudn\u00FD, Vladim\u00EDr" . "RIV/00209805:_____/03:00008216!RIV/2004/GA0/L26004/N" .