. "Ondr\u00E1\u0161ek, Ji\u0159\u00ED" . "Prvn\u00ED transplantace jater v tehdej\u0161\u00ED \u010CSSR byla provedena v Brn\u011B 2.2.1983, transplantovan\u00FD pacient \u017Eije ji\u017E p\u0159es 30 let s norm\u00E1ln\u011B funguj\u00EDc\u00EDmi j\u00E1try a je jedn\u00EDm z nejd\u00E9le p\u0159e\u017E\u00EDvaj\u00EDc\u00EDch po transplantaci jater v Evrop\u011B. K v\u011Bt\u0161\u00EDmu rozvoji transplantace jarter v CKTCH Brno doch\u00E1z\u00ED od poloviny 90. let 20. stolet\u00ED. V sou\u010Dasnosti je transplantov\u00E1no p\u0159ibli\u017En\u011B 30 pacient\u016F ro\u010Dn\u011B, k 31.12.2012 bylo provedeno 451 transplantac\u00ED jater. Z\u00E1kladn\u00ED indikac\u00ED je cirh\u00F3za jater r\u016Fzn\u00E9 etiologie, p\u0159ib\u00FDv\u00E1 cirh\u00F3zy p\u0159i hepatitid\u011B C. Urgentn\u00ED transplantace jater (pro akutn\u00ED selh\u00E1n\u00ED jater nebo prim\u00E1rn\u00ED afunkci prvn\u00EDho jatern\u00EDho \u0161t\u011Bpu), byla provedena v 11% p\u0159\u00EDpad\u016F. Retransplantac\u00ED bylo k 31.12.2012 provedeno 18 s 50% 5let\u00FDm p\u0159e\u017Eit\u00EDm. Prim\u00E1rn\u00ED afunkce \u0161t\u011Bpu byla u 7 pacient\u016F (t.j. 1,5%). Jednolet\u00E9 p\u0159e\u017Eit\u00ED v\u0161ech pacient\u016F po transplantaci jater v CKTCH Brno je 92%, 5let\u00E9 80% a 10let\u00E9 71%. Statisticky v\u00FDznamn\u011B se v sou\u010Dasnosti zvy\u0161uje v\u011Bk p\u0159\u00EDjemce, v\u011Bk d\u00E1rce i doba \u010Dek\u00E1n\u00ED na transplantaci, zvl\u00E1\u0161t\u011B mal\u00ED p\u0159\u00EDjemci s v\u00E1hou pod 70 kg \u010Dekaj\u00ED v\u00FDznamn\u011B del\u0161\u00ED dobu (medi\u00E1n \u010Dek\u00E1n\u00ED 178 dn\u00ED). V CKTCH Brno bylo k 31.12.2012 provedeno 14 kombinovan\u00FDch simult\u00E1nn\u00EDch transplantac\u00ED (13 j\u00E1tra + ledvina a 1 kombinovan\u00E1 simult\u00E1nn\u00ED transplantace j\u00E1tra + srdce + ledvina v roce 2005.)" . "RIV/00209775:_____/13:#0000267" . . . "V" . "V\u00FDsledky transplantac\u00ED jater v Brn\u011B" . "Prvn\u00ED transplantace jater v tehdej\u0161\u00ED \u010CSSR byla provedena v Brn\u011B 2.2.1983, transplantovan\u00FD pacient \u017Eije ji\u017E p\u0159es 30 let s norm\u00E1ln\u011B funguj\u00EDc\u00EDmi j\u00E1try a je jedn\u00EDm z nejd\u00E9le p\u0159e\u017E\u00EDvaj\u00EDc\u00EDch po transplantaci jater v Evrop\u011B. K v\u011Bt\u0161\u00EDmu rozvoji transplantace jarter v CKTCH Brno doch\u00E1z\u00ED od poloviny 90. let 20. stolet\u00ED. V sou\u010Dasnosti je transplantov\u00E1no p\u0159ibli\u017En\u011B 30 pacient\u016F ro\u010Dn\u011B, k 31.12.2012 bylo provedeno 451 transplantac\u00ED jater. Z\u00E1kladn\u00ED indikac\u00ED je cirh\u00F3za jater r\u016Fzn\u00E9 etiologie, p\u0159ib\u00FDv\u00E1 cirh\u00F3zy p\u0159i hepatitid\u011B C. Urgentn\u00ED transplantace jater (pro akutn\u00ED selh\u00E1n\u00ED jater nebo prim\u00E1rn\u00ED afunkci prvn\u00EDho jatern\u00EDho \u0161t\u011Bpu), byla provedena v 11% p\u0159\u00EDpad\u016F. Retransplantac\u00ED bylo k 31.12.2012 provedeno 18 s 50% 5let\u00FDm p\u0159e\u017Eit\u00EDm. Prim\u00E1rn\u00ED afunkce \u0161t\u011Bpu byla u 7 pacient\u016F (t.j. 1,5%). Jednolet\u00E9 p\u0159e\u017Eit\u00ED v\u0161ech pacient\u016F po transplantaci jater v CKTCH Brno je 92%, 5let\u00E9 80% a 10let\u00E9 71%. Statisticky v\u00FDznamn\u011B se v sou\u010Dasnosti zvy\u0161uje v\u011Bk p\u0159\u00EDjemce, v\u011Bk d\u00E1rce i doba \u010Dek\u00E1n\u00ED na transplantaci, zvl\u00E1\u0161t\u011B mal\u00ED p\u0159\u00EDjemci s v\u00E1hou pod 70 kg \u010Dekaj\u00ED v\u00FDznamn\u011B del\u0161\u00ED dobu (medi\u00E1n \u010Dek\u00E1n\u00ED 178 dn\u00ED). V CKTCH Brno bylo k 31.12.2012 provedeno 14 kombinovan\u00FDch simult\u00E1nn\u00EDch transplantac\u00ED (13 j\u00E1tra + ledvina a 1 kombinovan\u00E1 simult\u00E1nn\u00ED transplantace j\u00E1tra + srdce + ledvina v roce 2005.)"@cs . "5"^^ . . . "Liver transplant outcomes in Brno"@en . "RIV/00209775:_____/13:#0000267!RIV14-MZ0-00209775" . "0042-773X" . . . . "Husov\u00E1, Libu\u0161e" . "Mejzl\u00EDk, Vladim\u00EDr" . . . "The first liver transplant in the former Czechoslovakia took place in Brno on 2 February 1983; the patient concerned has lived for more than 30 years with a normally functioning liver and is one of the longest surviving patients after a liver transplant in Europe. The Cardiovascular and Transplantation Surgery Centre (CTSC) in Brno has experienced an increased development in the area of liver transplants since the mid-1990s. At present, about 30 patients a year undergo a transplantation, with 451 liver transplants in total as of 31 December 2012. The primary indication concerns liver cirrhosis of various etiologies, with an increasing number of cases of cirrhosis resulting from hepatitis C. Urgent liver transplants (for acute liver failure or primary dysfunction of first liver graft) amount to 11% of cases. There were 18 re-transplants performed as of 31 December 2012, with 50% five-year survival. The primary graft dysfunction was present in seven patients (i.e. 1.5%). The one-year survival rate of all patients after a liver transplant performed in CTSC is 92%, five-year survival rate is 80%, and ten-year survival rate is 71%. Currently the parameters such as recipient\u00B4s age, donor\u00B4s age, and transplant waiting time has been statistically increasing; small recipient\u00B4s with a body weight below 70 kg especially have to wait for a significantly longer period of time (waiting median of 178 days). In CTSC Brno 14 combined simultaneous transplants (13 transplants of liver + kidney and one combined simultaneous transplants of liver + heart + kidney in 2005) have been performed as of 31 December 2012."@en . "N\u011Bmec, Petr" . . "Vnit\u0159n\u00ED l\u00E9ka\u0159stv\u00ED" . . "8" . . "115751" . . . . "\u0160t\u011Bp\u00E1nkov\u00E1, So\u0148a" . "[50F87582C581]" . "liver transplant; outcomes; survival rate; combined simultaneous transplant of liver + heart + kidney"@en . . . "59" . "CZ - \u010Cesk\u00E1 republika" . "6"^^ . "V\u00FDsledky transplantac\u00ED jater v Brn\u011B" . "Kuman, Milan" . "V\u00FDsledky transplantac\u00ED jater v Brn\u011B"@cs . "Liver transplant outcomes in Brno"@en . . "6"^^ . "V\u00FDsledky transplantac\u00ED jater v Brn\u011B"@cs . . .