"Karcinom pankreatu je agresivn\u00ED n\u00E1dorov\u00E9 onemocn\u011Bn\u00ED, kter\u00E9 m\u00E1 zvy\u0161uj\u00EDc\u00ED se incidenci. Radik\u00E1ln\u00ED resekce, kter\u00E1 jedin\u00E1 je potenci\u00E1ln\u011B kurabiln\u00ED metodou l\u00E9\u010Dby, je mo\u017En\u00E1 pouze u 20-30% pacient\u016F. Hlavn\u00EDmi symptomy, kter\u00E9 obt\u011B\u017Euj\u00ED pacienty s pokro\u010Dil\u00FDm neresekabiln\u00EDm karcinomem hlavy pankreatu a periampul\u00E1rn\u00ED oblasti, jsou obstruk\u010Dn\u00ED ikterus p\u0159i sten\u00F3ze dist\u00E1ln\u00EDho choledochu, vysok\u00FD ileus p\u0159i sten\u00F3ze duodena a bolesti, zejm\u00E9na epigastria a v z\u00E1dech. Smyslem paliativn\u00ED l\u00E9\u010Dby je zm\u00EDrn\u011Bn\u00ED t\u011Bchto obt\u00ED\u017E\u00ED. C\u00EDlem na\u0161eho sd\u011Blen\u00ED je zhodnotit vlastn\u00ED v\u00FDsledky paliativn\u00ED chirurgick\u00E9 l\u00E9\u010Dby malign\u00EDho onemocn\u011Bn\u00ED pankreatu a periampul\u00E1rn\u00ED oblasti. Do souboru jsme za\u0159adili pacienty s karcinomem pankreatu a periampul\u00E1rn\u00ED oblasti, kter\u00E9 jsme operovali na Chirurgick\u00E9 klinice FN Hradec Kr\u00E1lov\u00E9 od 1.1.2006 do 31.12.2010. V\u00FDhodou chirurgicky proveden\u00E9 hepatiko-jejuno anastom\u00F3zy oproti zav\u00E1d\u011Bn\u00ED endoskopick\u00FDch stent\u016F je zejm\u00E9na lep\u0161\u00ED dlouhodob\u00E1 pr\u016Fchodnost, proto je vhodn\u00E9 tuto operaci prov\u00E1d\u011Bt u pacient\u016F s del\u0161\u00EDm p\u0159edpokl\u00E1dan\u00FDm p\u0159e\u017Eit\u00EDm. Morbidita spojkov\u00FDch operac\u00ED je vcelku n\u00EDzk\u00E1 a 30denn\u00ED poopera\u010Dn\u00ED letalita v na\u0161em souboru nulov\u00E1." . "Pancreatic cancer is an aggressive malignant disease with increasing incidence. Radical resection, the only potentially curative method, is possible in only 20-30% of patients. The main symptoms of advanced non-resectable pancreatic head tumors include obstructive jaundice, caused by stenosis of distal common bile duct, duodenal obstruction and pain, especially in the epigastric region and back. The aim of palliative treatment is to relieve these complaints. This paper evaluates our own palliative surgical treatment results in patients with pancreatic head and periampullary region cancer. This study included all patienst with pancreatic head and periampullary region cancer who underwent surgery at the Department of Surgery, University Hospital in Hradec Kralove from 1st January 2006 to 31st December 2010. The advantage of surgical hepatico-jejuno anastomosis over endoscopically placed stent is particulary in superior long-term patency. Therefore, it is advisable to perform these procedures in patients with longer expected survival. Morbidity associated with palliative surgical procedures was relatively low and there was no mortality."@en . "Palliative Surgical Treatment of Tumors of Pancreas and Periampullary Region"@en . . . "\u0160ubrt, Zden\u011Bk" . "quality of life; survival; palliative surgery; palliative care; pancreatic cancer"@en . "25" . "RIV/00179906:_____/12:10131021" . . . . . "0862-495X" . "[8FCA62F74706]" . . "I, P(NS9998)" . "RIV/00179906:_____/12:10131021!RIV13-MZ0-00179906" . . . . . "157630" . . . "\u010Ce\u010Dka, Filip" . . "2" . "Paliativn\u00ED chirurgick\u00E1 l\u00E9\u010Dba n\u00E1dor\u016F pankreatu a periampul\u00E1rn\u00ED oblasti" . "Ferko, Alexander" . . "Paliativn\u00ED chirurgick\u00E1 l\u00E9\u010Dba n\u00E1dor\u016F pankreatu a periampul\u00E1rn\u00ED oblasti"@cs . . "Karcinom pankreatu je agresivn\u00ED n\u00E1dorov\u00E9 onemocn\u011Bn\u00ED, kter\u00E9 m\u00E1 zvy\u0161uj\u00EDc\u00ED se incidenci. Radik\u00E1ln\u00ED resekce, kter\u00E1 jedin\u00E1 je potenci\u00E1ln\u011B kurabiln\u00ED metodou l\u00E9\u010Dby, je mo\u017En\u00E1 pouze u 20-30% pacient\u016F. Hlavn\u00EDmi symptomy, kter\u00E9 obt\u011B\u017Euj\u00ED pacienty s pokro\u010Dil\u00FDm neresekabiln\u00EDm karcinomem hlavy pankreatu a periampul\u00E1rn\u00ED oblasti, jsou obstruk\u010Dn\u00ED ikterus p\u0159i sten\u00F3ze dist\u00E1ln\u00EDho choledochu, vysok\u00FD ileus p\u0159i sten\u00F3ze duodena a bolesti, zejm\u00E9na epigastria a v z\u00E1dech. Smyslem paliativn\u00ED l\u00E9\u010Dby je zm\u00EDrn\u011Bn\u00ED t\u011Bchto obt\u00ED\u017E\u00ED. C\u00EDlem na\u0161eho sd\u011Blen\u00ED je zhodnotit vlastn\u00ED v\u00FDsledky paliativn\u00ED chirurgick\u00E9 l\u00E9\u010Dby malign\u00EDho onemocn\u011Bn\u00ED pankreatu a periampul\u00E1rn\u00ED oblasti. Do souboru jsme za\u0159adili pacienty s karcinomem pankreatu a periampul\u00E1rn\u00ED oblasti, kter\u00E9 jsme operovali na Chirurgick\u00E9 klinice FN Hradec Kr\u00E1lov\u00E9 od 1.1.2006 do 31.12.2010. V\u00FDhodou chirurgicky proveden\u00E9 hepatiko-jejuno anastom\u00F3zy oproti zav\u00E1d\u011Bn\u00ED endoskopick\u00FDch stent\u016F je zejm\u00E9na lep\u0161\u00ED dlouhodob\u00E1 pr\u016Fchodnost, proto je vhodn\u00E9 tuto operaci prov\u00E1d\u011Bt u pacient\u016F s del\u0161\u00EDm p\u0159edpokl\u00E1dan\u00FDm p\u0159e\u017Eit\u00EDm. Morbidita spojkov\u00FDch operac\u00ED je vcelku n\u00EDzk\u00E1 a 30denn\u00ED poopera\u010Dn\u00ED letalita v na\u0161em souboru nulov\u00E1."@cs . . . "Palliative Surgical Treatment of Tumors of Pancreas and Periampullary Region"@en . "Jon, Bohumil" . . "CZ - \u010Cesk\u00E1 republika" . "Paliativn\u00ED chirurgick\u00E1 l\u00E9\u010Dba n\u00E1dor\u016F pankreatu a periampul\u00E1rn\u00ED oblasti" . . "Dvo\u0159\u00E1k, Josef" . "6"^^ . "Klinick\u00E1 onkologie" . . "6"^^ . . "Paliativn\u00ED chirurgick\u00E1 l\u00E9\u010Dba n\u00E1dor\u016F pankreatu a periampul\u00E1rn\u00ED oblasti"@cs . "Rep\u00E1k, Rudolf" . . . "7"^^ .