. "Autofagie a jej\u00ED \u00FAloha v obrann\u00E9 a po\u0161kozuj\u00EDc\u00ED z\u00E1n\u011Btov\u00E9 reakci"@cs . . . "124160" . . "CZ - \u010Cesk\u00E1 republika" . "Berglov\u00E1, Irena" . "Andr\u00FDs, Ctirad" . . . . "\u010Casopis l\u00E9ka\u0159\u016F \u010Desk\u00FDch" . "Autofagie a jej\u00ED \u00FAloha v obrann\u00E9 a po\u0161kozuj\u00EDc\u00ED z\u00E1n\u011Btov\u00E9 reakci" . . . "Autophagy and its role in protective and damaging inflammatory response"@en . "Holmannov\u00E1, Drahom\u00EDra" . "Autofagie a jej\u00ED \u00FAloha v obrann\u00E9 a po\u0161kozuj\u00EDc\u00ED z\u00E1n\u011Btov\u00E9 reakci"@cs . "AbuAttieh, Mouhammed Omar" . "I, S, Z(MSM0021620812)" . "RIV/00179906:_____/12:10123926" . "0008-7335" . "6"^^ . "Hrn\u010D\u00ED\u0159ov\u00E1, Lucia" . . . . "RIV/00179906:_____/12:10123926!RIV13-MZ0-00179906" . "Autofagie a jej\u00ED \u00FAloha v obrann\u00E9 a po\u0161kozuj\u00EDc\u00ED z\u00E1n\u011Btov\u00E9 reakci" . . . "3"^^ . . . . "Krejsek, Jan" . . "Autofagie je sou\u010D\u00E1st\u00ED biologick\u00E9 strategie bu\u0148ky p\u0159ekonat nep\u0159\u00EDzniv\u00E9 \u017Eivotn\u00ED podm\u00EDnky. Je v\u00FDznamnou slo\u017Ekou obrany cytoplazmatick\u00E9ho kompartmentu bu\u0148ky p\u0159ed intracelul\u00E1rn\u00EDmi patogeny. Abnormity v autofagii jsou jednou z p\u0159\u00ED\u010Din nedostate\u010Dn\u00E9 kontroly mikrobiomu st\u0159eva nemocn\u00FDch s Crohnovou chorobou a pod\u00EDlej\u00ED se na jej\u00ED imunopatogenezi. Deregulace autofagie p\u0159isp\u00EDv\u00E1 k p\u0159e\u017E\u00EDv\u00E1n\u00ED autoreaktivn\u00EDch T lymfocyt\u016F a uplat\u0148uje se tak v imunopatogenezi roztrou\u0161en\u00E9 skler\u00F3zy." . "Crohn's disease; multiple sclerosis; inflammation; immunity; autophagy"@en . "2" . "151" . . . "Autophagy and its role in protective and damaging inflammatory response"@en . . "7"^^ . "[E218988598E3]" . "Autofagie je sou\u010D\u00E1st\u00ED biologick\u00E9 strategie bu\u0148ky p\u0159ekonat nep\u0159\u00EDzniv\u00E9 \u017Eivotn\u00ED podm\u00EDnky. Je v\u00FDznamnou slo\u017Ekou obrany cytoplazmatick\u00E9ho kompartmentu bu\u0148ky p\u0159ed intracelul\u00E1rn\u00EDmi patogeny. Abnormity v autofagii jsou jednou z p\u0159\u00ED\u010Din nedostate\u010Dn\u00E9 kontroly mikrobiomu st\u0159eva nemocn\u00FDch s Crohnovou chorobou a pod\u00EDlej\u00ED se na jej\u00ED imunopatogenezi. Deregulace autofagie p\u0159isp\u00EDv\u00E1 k p\u0159e\u017E\u00EDv\u00E1n\u00ED autoreaktivn\u00EDch T lymfocyt\u016F a uplat\u0148uje se tak v imunopatogenezi roztrou\u0161en\u00E9 skler\u00F3zy."@cs . . "Autophagy is an itegral part of cell strategy to overcome adverse living conditions. Moreover, autophagy participates in the protection of cytoplasma against invasion of the intracellular pathogenic bacteria. Abnormalities in the autophagy are participating on the inability of Crohn's disease patients to mantain gut microbiome homeostasis ultimating in the development of immunopathological reaction in these patients. Autophagy can enhance the survival of autoreactive T cells in multiple sclerosis patients thus contributing to the disease induction and progression."@en .