"28"^^ . "SAR; oxime; reactivation; insecticide; pesticide; acetylcholinesterase"@en . . "Design, evaluation and structure-activity relationship studies of the AChE reactivators against organophosphorus pesticides" . . "Design, evaluation and structure-activity relationship studies of the AChE reactivators against organophosphorus pesticides" . "Design, evaluation and structure-activity relationship studies of the AChE reactivators against organophosphorus pesticides"@en . "4" . . "During the last two decades, the treatment of OPP exposure has become more widely discussed because of growing agricultural production, industrialisation and harmful social issues (e.g. suicides). In this review is summarised the design, evaluation and structure-activity relationship studies of recently produced AChE reactivators. Since pralidoxime, over 300 oximes have been produced or tested against OPP poisoning, and several novel compounds show very promising abilities as comparable (or higher) to commercial oximes. Some of these are highlighted for their further testing of OPP exposure, and additionally, the main structure-activity relationship of AChE reactivators against OPP are discussed."@en . "Dole\u017Eal, Martin" . . "193530" . "During the last two decades, the treatment of OPP exposure has become more widely discussed because of growing agricultural production, industrialisation and harmful social issues (e.g. suicides). In this review is summarised the design, evaluation and structure-activity relationship studies of recently produced AChE reactivators. Since pralidoxime, over 300 oximes have been produced or tested against OPP poisoning, and several novel compounds show very promising abilities as comparable (or higher) to commercial oximes. Some of these are highlighted for their further testing of OPP exposure, and additionally, the main structure-activity relationship of AChE reactivators against OPP are discussed." . "31" . "RIV/00179906:_____/11:10099227" . . "Medicinal Research Reviews" . "4"^^ . . "000292570100003" . . . "http://onlinelibrary.wiley.com/doi/10.1002/med.20192/pdf" . "0198-6325" . "Mus\u00EDlek, Kamil" . . "Gunn-Moore, Frank" . . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . . . . . . "1"^^ . . . "I, P(ME09086)" . "10.1002/med.20192" . "Design, evaluation and structure-activity relationship studies of the AChE reactivators against organophosphorus pesticides"@en . . . . "RIV/00179906:_____/11:10099227!RIV13-MZ0-00179906" . "Ku\u010Da, Kamil" . "[FBE1A09EAE2F]" .