"Up-regulation of the Apo/Fas (CD95) complex on neutrophils harvested during cardiac surgery: distinct findings in patients operated on with or without the use of cardiopulmonary bypass"@en . "1" . . "25" . . . "000275458800008" . . . "Man\u010F\u00E1k, Ji\u0159\u00ED" . . "294493" . "apoptosis; Apo/Fas complex; neutrophil; inflammation; cardiac surgery"@en . "[DA17DA3D4023]" . . . . . "In %22on-pump%22 patients, we found an increase in the expression of CD95 median intensity fluorescence (MFI) on granulocytes from a baseline level median=56, (Q 1=45.5, Q3=64) to a median=88, (Q1=62, Q 3=109.5; p{0.01) at the 3rd postoperative day and median=74, (Q1=63, Q3=84.5; p{0.01) at the 7th postoperative day. In %22off-pump%22 patients, granulocyte CD95 MFI was median=55, (Q1=51, Q3=84) before surgery. The significant increase was found on the 3rd postoperative day only; median=90, (Q 1=66; Q3=98; p{0.05). A similar pattern in the CD95 expression was also found if percentage changes of granulocyte CD95 MFI were followed. Moreover, the significantly increased Apo/Fas expression expressed as a percentage change of CD95 MFI was found in %22on-pump%22 patients compared to %22off-pump%22 patients, both at the 3rd postoperative day (p{0.05) and at the 7th postoperative day (p{0.01).10.1177/0267659110363318"@en . "Andr\u00FDs, Ctirad" . . . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . "In %22on-pump%22 patients, we found an increase in the expression of CD95 median intensity fluorescence (MFI) on granulocytes from a baseline level median=56, (Q 1=45.5, Q3=64) to a median=88, (Q1=62, Q 3=109.5; p{0.01) at the 3rd postoperative day and median=74, (Q1=63, Q3=84.5; p{0.01) at the 7th postoperative day. In %22off-pump%22 patients, granulocyte CD95 MFI was median=55, (Q1=51, Q3=84) before surgery. The significant increase was found on the 3rd postoperative day only; median=90, (Q 1=66; Q3=98; p{0.05). A similar pattern in the CD95 expression was also found if percentage changes of granulocyte CD95 MFI were followed. Moreover, the significantly increased Apo/Fas expression expressed as a percentage change of CD95 MFI was found in %22on-pump%22 patients compared to %22off-pump%22 patients, both at the 3rd postoperative day (p{0.05) and at the 7th postoperative day (p{0.01).10.1177/0267659110363318" . . . . "Up-regulation of the Apo/Fas (CD95) complex on neutrophils harvested during cardiac surgery: distinct findings in patients operated on with or without the use of cardiopulmonary bypass" . "P(NR9090), Z(MSM0021620812)" . "7"^^ . . . "Up-regulation of the Apo/Fas (CD95) complex on neutrophils harvested during cardiac surgery: distinct findings in patients operated on with or without the use of cardiopulmonary bypass"@en . . "Harrer, Jan" . . . . "RIV/00179906:_____/10:10069732" . "5"^^ . . "Perfusion" . "RIV/00179906:_____/10:10069732!RIV11-MZ0-00179906" . "0267-6591" . "6"^^ . "Kune\u0161, Pavel" . "Krejsek, Jan" . "Up-regulation of the Apo/Fas (CD95) complex on neutrophils harvested during cardiac surgery: distinct findings in patients operated on with or without the use of cardiopulmonary bypass" . "Kol\u00E1\u010Dkov\u00E1, Martina" . . "Holick\u00E1, Monika" .