"Studies of an ERP negative amplitude deflection elicited by a change in a series of auditory stimuli is known as mismatch negativity (MMN). The generation of MMN is impaired in schizophrenia. Its deficit is associated with lower everyday functioning and may be also interpreted as the marker of progression in schizophrenia. MMN elicited by visual stimuli (vMMN) was described by several research teams, but it has not been investigated in schizophrenia as yet. Using a motion-direction paradigm, we elicited visual MMN in 24 patients with schizophrenia and schizoaffective disorder. They were compared between groups of patients with schizophrenia and healthy controls. The significantly smaller vMMN indicated an impaired generation of MMN in patients with schizophrenia. In secondary analyses there was an association of vMMN impairment among patients with higher dose of medication, lower level of functioning and the presence of deficit syndrome." . . . "RIV/00179906:_____/08:00001309" . . "Zrakov\u00E1 mismatch negativita u pacient\u016F se schizofreni\u00ED"@cs . "1-3" . . . "Visual mismatch negativity among patients with schizophrenia"@en . "S, Z(MSM0021620816)" . "Urban, Ale\u0161" . . "NL - Nizozemsko" . "Masopust, Ji\u0159\u00ED" . . "Visual mismatch negativity among patients with schizophrenia" . . . . . "402805" . . . "Visual mismatch negativity among patients with schizophrenia" . "0920-9964" . . "schizophrenia; event related potentials; mismatch negativity; visual mismatch negativity; information processing"@en . "9"^^ . "Kreml\u00E1\u010Dek, Jan" . . "Libiger, Jan" . "3"^^ . "Schizophrenia Research" . "102" . . "Studie negativn\u00ED komponenty ERP vyvolan\u00E9 zm\u011Bnou v s\u00E9rii uniformn\u00EDch zvukov\u00FDch podn\u011Bt\u016F je zn\u00E1ma jako mismatch negativita (MMN). U pacient\u016F se schizofreni\u00ED je jej\u00ED generov\u00E1n\u00ED deficitn\u00ED. Tento deficit je spojen se zhor\u0161en\u00FDm ka\u017Edodenn\u00EDm fungov\u00E1n\u00EDm a m\u016F\u017Ee b\u00FDt interpretov\u00E1n jako marker progrese schizofrenn\u00EDho onemocn\u011Bn\u00ED. MMN vyvolan\u00E1 zrakov\u00FDmi podn\u011Bty (vMMN) byla pops\u00E1na n\u011Bkolika v\u00FDzkumn\u00FDmi t\u00FDmy, ale u pacient\u016F se schizofreni\u00ED dosud studov\u00E1na nebyla. Pou\u017Eit\u00EDm pohybov\u00FDch stimulac\u00ED jsme vyvolali zrakovou MMN u 24 pacient\u016F se schizofreni\u00ED. Skupinu pacient\u016F jsem porovnali se skupinou zdrav\u00FDch kontrol. U skupiny nemocn\u00FDch byla zji\u0161t\u011Bna statisticky v\u00FDznamn\u011B men\u0161\u00ED vMMN. V dal\u0161\u00EDch anal\u00FDz\u00E1ch byl zji\u0161t\u011Bn vztah mezi deficitn\u00ED vMMN a vy\u0161\u0161\u00ED d\u00E1vkou medikace, ni\u017E\u0161\u00ED \u00FArovn\u00ED fungov\u00E1n\u00ED a p\u0159\u00EDtomnost\u00ED deficitn\u00EDho syndromu. Toto posti\u017Een\u00ED se zd\u00E1 b\u00FDt analogick\u00E9 posti\u017Een\u00ED MMN v auditivn\u00ED oblasti a pravd\u011Bpodobn\u011B se vztahuje k \u010Dasn\u00E9 f\u00E1zi zpracov\u00E1n\u00ED zrakov\u00FDch informac\u00ED."@cs . "RIV/00179906:_____/08:00001309!RIV09-MSM-00179906" . . "Zrakov\u00E1 mismatch negativita u pacient\u016F se schizofreni\u00ED"@cs . . "Studies of an ERP negative amplitude deflection elicited by a change in a series of auditory stimuli is known as mismatch negativity (MMN). The generation of MMN is impaired in schizophrenia. Its deficit is associated with lower everyday functioning and may be also interpreted as the marker of progression in schizophrenia. MMN elicited by visual stimuli (vMMN) was described by several research teams, but it has not been investigated in schizophrenia as yet. Using a motion-direction paradigm, we elicited visual MMN in 24 patients with schizophrenia and schizoaffective disorder. They were compared between groups of patients with schizophrenia and healthy controls. The significantly smaller vMMN indicated an impaired generation of MMN in patients with schizophrenia. In secondary analyses there was an association of vMMN impairment among patients with higher dose of medication, lower level of functioning and the presence of deficit syndrome."@en . "4"^^ . . "[FB24ACD23C70]" . . "000257837700037" . "Visual mismatch negativity among patients with schizophrenia"@en .