. "1"^^ . "Invega-paliperidon ER tablety s prodlou\u017Een\u00FDm uvol\u0148ov\u00E1n\u00EDm" . "Invega-paliperidon ER tablety s prodlou\u017Een\u00FDm uvol\u0148ov\u00E1n\u00EDm"@cs . . . . . . "5"^^ . "4" . "Invega-paliperidon ER tablety s prodlou\u017Een\u00FDm uvol\u0148ov\u00E1n\u00EDm"@cs . "Invega-paliperidon ER tablety s prodlou\u017Een\u00FDm uvol\u0148ov\u00E1n\u00EDm" . "[BDA2056B7A9E]" . . "373157" . . . "Paliperidone tablets with extended release is a new antipsychotic drug registered for the treatment of schizophrenia. Paliperidone 9 hydroxy risperidone is an active metabolite of risperidone. The OROS (osmotic controlled-release oral delivery system) technology provides extended release of active substance and relatively stabile plasmatic level of the drug. Clinical efficacy is comparable with risperidone. Paliperidone ER tablets are well tolerated and have simple dosage regimen."@en . "Invega-paliperidone ER tablets with extended relesase"@en . "5" . "RIV/00179906:_____/08:00001305" . . . "Praktick\u00E9 l\u00E9k\u00E1renstv\u00ED" . . "antipsychotics; paliperidon; schizophrenia"@en . "Z(MSM0021620816)" . . "Paliperidon tablety s pozvoln\u00FDm uvol\u0148ov\u00E1n\u00EDm je nov\u00E9 antipsychotikum registrovan\u00E9 v indikaci l\u00E9\u010Dby schizofrenie. Paliperidon 9 hydroxyrisperidon je aktivn\u00EDm metabolitem antipsychotika druh\u00E9 generace risperidonu. Tableta p\u0159ipraven\u00E1 v OROS (osmotic controlled-release oral delivery system) technologii zaji\u0161\u0165uje pozvoln\u00E9 uvol\u0148ov\u00E1n\u00ED aktivn\u00ED l\u00E1tky v pr\u016Fb\u011Bhu pas\u00E1\u017Ee tablety gastrointestin\u00E1ln\u00EDm traktem. Tableta proto nesm\u00ED b\u00FDt p\u016Flena nebo rozkousnuta. OROS forma zaji\u0161\u0165uje relativn\u011B stabiln\u00ED plazmatickou hladinu l\u00E9ku. Dlouh\u00FD polo\u010Das vylu\u010Dov\u00E1n\u00ED umo\u017E\u0148uje jednoduch\u00E9 d\u00E1vkov\u00E1n\u00ED jednou denn\u011B v rann\u00ED d\u00E1vce. Klinick\u00FD efekt srovnateln\u00FD s mate\u0159skou molekulou risperidonu, relativn\u011B p\u0159\u00EDzniv\u011Bj\u0161\u00ED profil ne\u017E\u00E1douc\u00EDch \u00FA\u010Dink\u016F a jednoduch\u00E9 d\u00E1vkov\u00E1n\u00ED zvy\u0161uj\u00ED \u0161anci na zlep\u0161en\u00ED adherence psychotick\u00FDch pacient\u016F k l\u00E9\u010Db\u011B."@cs . "T\u016Fma, Ivan" . "CZ - \u010Cesk\u00E1 republika" . "1801-2434" . "RIV/00179906:_____/08:00001305!RIV09-MSM-00179906" . "Invega-paliperidone ER tablets with extended relesase"@en . . . "Paliperidon tablety s pozvoln\u00FDm uvol\u0148ov\u00E1n\u00EDm je nov\u00E9 antipsychotikum registrovan\u00E9 v indikaci l\u00E9\u010Dby schizofrenie. Paliperidon 9 hydroxyrisperidon je aktivn\u00EDm metabolitem antipsychotika druh\u00E9 generace risperidonu. Tableta p\u0159ipraven\u00E1 v OROS (osmotic controlled-release oral delivery system) technologii zaji\u0161\u0165uje pozvoln\u00E9 uvol\u0148ov\u00E1n\u00ED aktivn\u00ED l\u00E1tky v pr\u016Fb\u011Bhu pas\u00E1\u017Ee tablety gastrointestin\u00E1ln\u00EDm traktem. Tableta proto nesm\u00ED b\u00FDt p\u016Flena nebo rozkousnuta. OROS forma zaji\u0161\u0165uje relativn\u011B stabiln\u00ED plazmatickou hladinu l\u00E9ku. Dlouh\u00FD polo\u010Das vylu\u010Dov\u00E1n\u00ED umo\u017E\u0148uje jednoduch\u00E9 d\u00E1vkov\u00E1n\u00ED jednou denn\u011B v rann\u00ED d\u00E1vce. Klinick\u00FD efekt srovnateln\u00FD s mate\u0159skou molekulou risperidonu, relativn\u011B p\u0159\u00EDzniv\u011Bj\u0161\u00ED profil ne\u017E\u00E1douc\u00EDch \u00FA\u010Dink\u016F a jednoduch\u00E9 d\u00E1vkov\u00E1n\u00ED zvy\u0161uj\u00ED \u0161anci na zlep\u0161en\u00ED adherence psychotick\u00FDch pacient\u016F k l\u00E9\u010Db\u011B." . "1"^^ .