"4"^^ . . "Nestin, vimentin and GFAP coexpression in reactive astrocytes in response to the striatal neurotoxic lesion"@en . . "Hradec Kr\u00E1lov\u00E9" . . . "4"^^ . "UK. Farmaceutick\u00E1 fakulta" . . "978-80-254-1310-4" . "Nestin, vimentin and GFAP coexpression in reactive astrocytes in response to the striatal neurotoxic lesion"@en . . "L\u00E1tr, Ivan" . . . "[020A041CF6B6]" . "Koexprese nestinu, vimentinu a GFAP v reaktivn\u00EDch astrocytech v odpov\u011Bdi na neurotoxickou l\u00E9zi striata"@cs . "RIV/00179906:_____/08:00001253!RIV09-MSM-00179906" . "In our study, we have demonstrated the immediate reaction of reactive astrocytes to the neurotoxic damage within the striatum by immunohistochemical detection. The most interesting finding was gradual reexpression of those intermediate filaments (IFs) which are not present in astrocytes within the intact brain because they are typical only for undifferentiated or less differentiated neural cells. Very interesting was intensive and increased coexpression of all three IFs in vascular end-feet which confirmed specialized relationship of astrocytes to the blood vessels (also in relation to the hemato-encephalic barrier) - the existence of glio-vascular unit."@en . . "Gun\u010Dov\u00E1, Ivana" . "RIV/00179906:_____/08:00001253" . . "reactive astrocytes; immediate reaction; neurotoxic damage; intermediate filaments"@en . "V na\u0161\u00ED pr\u00E1ci jsme pomoc\u00ED imunohistochemick\u00E9 detekce spektra marker\u016F charakterizovali reaktivn\u00ED astrocyty v akutn\u00ED f\u00E1zi rozvoje neurodegenerativn\u00EDho po\u0161kozen\u00ED striata. Hlavn\u00EDm n\u00E1lezem byla postupn\u00E1 reexprese intermedi\u00E1ln\u00EDch filament (IF), kter\u00E9 se v astrocytech intaktn\u00EDch zv\u00ED\u0159at v\u016Fbec nevyskytuj\u00ED, proto\u017Ee jsou charakteristick\u00E9 pro nediferencovan\u00E9 nebo m\u00E1lo diferencovan\u00E9 neur\u00E1ln\u00ED bu\u0148ky. Nejv\u00FDrazn\u011Bj\u0161\u00ED, nar\u016Fstaj\u00EDc\u00ED koexprese v\u0161ech t\u0159\u00ED IF byla ve vaskul\u00E1rn\u00EDch no\u017Ek\u00E1ch astrocyt\u016F - to potvrzuje specializovan\u00FD vztah astrocyt\u016F ke st\u011Bn\u011B c\u00E9v - tzv. gliovaskul\u00E1rn\u00ED jednotka."@cs . "Koexprese nestinu, vimentinu a GFAP v reaktivn\u00EDch astrocytech v odpov\u011Bdi na neurotoxickou l\u00E9zi striata" . "Z(MSM0021620820)" . . . "2. morfologick\u00FD postgradu\u00E1ln\u00ED kurz" . "Koexprese nestinu, vimentinu a GFAP v reaktivn\u00EDch astrocytech v odpov\u011Bdi na neurotoxickou l\u00E9zi striata"@cs . . "1"^^ . . . "V na\u0161\u00ED pr\u00E1ci jsme pomoc\u00ED imunohistochemick\u00E9 detekce spektra marker\u016F charakterizovali reaktivn\u00ED astrocyty v akutn\u00ED f\u00E1zi rozvoje neurodegenerativn\u00EDho po\u0161kozen\u00ED striata. Hlavn\u00EDm n\u00E1lezem byla postupn\u00E1 reexprese intermedi\u00E1ln\u00EDch filament (IF), kter\u00E9 se v astrocytech intaktn\u00EDch zv\u00ED\u0159at v\u016Fbec nevyskytuj\u00ED, proto\u017Ee jsou charakteristick\u00E9 pro nediferencovan\u00E9 nebo m\u00E1lo diferencovan\u00E9 neur\u00E1ln\u00ED bu\u0148ky. Nejv\u00FDrazn\u011Bj\u0161\u00ED, nar\u016Fstaj\u00EDc\u00ED koexprese v\u0161ech t\u0159\u00ED IF byla ve vaskul\u00E1rn\u00EDch no\u017Ek\u00E1ch astrocyt\u016F - to potvrzuje specializovan\u00FD vztah astrocyt\u016F ke st\u011Bn\u011B c\u00E9v - tzv. gliovaskul\u00E1rn\u00ED jednotka." . "Koexprese nestinu, vimentinu a GFAP v reaktivn\u00EDch astrocytech v odpov\u011Bdi na neurotoxickou l\u00E9zi striata" . . "374987" . "Rudolf, Emil" . "Mazurov\u00E1, Yvona" .