"0172-780X" . "The COMT Val158Met polymorphism is associated with novelty seeking in Czech methamphetamine abusers: Preliminary results"@en . "[7B650B5359CA]" . . "methamphetamine dependence; novelty-seeking behavior; COMT; COMT Gene Val158Met polymorphism; dopamine"@en . "The COMT Val158Met polymorphism is associated with novelty seeking in Czech methamphetamine abusers: Preliminary results"@en . "RIV/00179906:_____/06:00000079!RIV07-MZ0-00179906" . "N\u011Bkter\u00E9 m\u011B\u0159iteln\u00E9 rysy lidsk\u00E9 osobnosti predisponuj\u00ED k rozvoji ur\u010Dit\u00E9 psychopatologie. Zv\u00FD\u0161en\u00E1 pot\u0159eba vyhled\u00E1vat nov\u00E9 podn\u011Bty (novelty seeking, NS) hraje v\u00FDznamnou roli v etiopatogenezi z\u00E1vislosti na n\u00E1vykov\u00FDch l\u00E1tk\u00E1ch. Povahov\u00FD rys NS m\u00E1 vztah k dopaminergn\u00ED neurotransmisi. Catechol-O-methyltransfer\u00E1za (COMT) je nezbytn\u00E1 p\u0159i odbour\u00E1v\u00E1n\u00ED dopaminu. C\u00EDlem na\u0161\u00ED pr\u00E1ce bylo zjistit, zda funk\u010Dn\u00ED polymorfismus Val158Met genu pro COMT m\u00E1 vztah ke sk\u00F3ru NS u osob, z\u00E1visl\u00FDch na pervitinu."@cs . . "6" . . "RIV/00179906:_____/06:00000079" . . . "27" . "Ber\u00E1nek, Martin" . "Measurable traits of human personality may mark the predispostion to psychopathology. Increase novelty seeking plays an important role in the pathogenesis of substance abuse. Novelty seeking, one of the fundamental traits of the human temperament, is relate to dopamine. Catechol-O-methyltransferase (COMT) is essential for dopamine inactivation. The aim of our study was to assess whether the COMT gene Val158Met functional polymorphism in patients dependent on methamphetamine is related to their novelty siiking score." . "4"^^ . "Measurable traits of human personality may mark the predispostion to psychopathology. Increase novelty seeking plays an important role in the pathogenesis of substance abuse. Novelty seeking, one of the fundamental traits of the human temperament, is relate to dopamine. Catechol-O-methyltransferase (COMT) is essential for dopamine inactivation. The aim of our study was to assess whether the COMT gene Val158Met functional polymorphism in patients dependent on methamphetamine is related to their novelty siiking score."@en . . "The COMT Val158Met polymorphism is associated with novelty seeking in Czech methamphetamine abusers: Preliminary results" . "SE - \u0160v\u00E9dsk\u00E9 kr\u00E1lovstv\u00ED" . . . . . . "Neuroendocrinology Letters" . . . . . "4"^^ . . "469532" . "Hos\u00E1k, Ladislav" . . "Libiger, Jan" . "Z(MZ0FNHK2005)" . . "Polymorfismus Val158Met genu pro COMT a novelty seeking u z\u00E1vislosti na pervitinu"@cs . . "\u010C\u00ED\u017Eek, Ji\u0159\u00ED" . "5"^^ . "Polymorfismus Val158Met genu pro COMT a novelty seeking u z\u00E1vislosti na pervitinu"@cs . . "The COMT Val158Met polymorphism is associated with novelty seeking in Czech methamphetamine abusers: Preliminary results" . "799;802" .