"[10FA3E2F24E2]" . "VYSAZOV\u00C1N\u00CD BENZODIAZEPIN\u016E U PACIENT\u016E S \u00DAZKOSTN\u00DDMI PORUCHAMI" . "Pra\u0161ko, J\u00E1n Pavlov" . "CZ - \u010Cesk\u00E1 republika" . . . . . "Discontinuation of benzodiazepines in patients with anxiety disorders"@en . . "1211-7579" . "Navzdory zv\u00FD\u0161en\u00E9 pozornosti k pod\u00E1v\u00E1n\u00ED antidepresiv a dal\u0161\u00EDch l\u00E9k\u016F k l\u00E9\u010Db\u011B \u00FAzkosti, benzodiazepiny z\u016Fst\u00E1vaj\u00ED nej\u010Dast\u011Bji p\u0159edepisovanou anxiolytickou medikaci pro jejich v\u00FDrazn\u00FD efekt, rychl\u00FD po\u010D\u00E1tek \u00FA\u010Dinku a v\u0161eobecn\u011B dobr\u00E9mu profilu ne\u017E\u00E1douc\u00EDch \u00FA\u010Dink\u016F. Jejich vysazen\u00ED po redukci \u00FAzkosti je prosp\u011B\u0161n\u00E9 proto\u017Ee dlouhodob\u00E9 u\u017E\u00EDv\u00E1n\u00ED souvis\u00ED s \u0159adou ne\u017E\u00E1douc\u00EDch jev\u016F. B\u011Bhem vysazov\u00E1n\u00ED se mohou objevit nov\u00E9 p\u0159\u00EDznaky \u00FAzkosti a to mnoh\u00FDm pacient\u016Fm br\u00E1n\u00ED ve vysazen\u00ED l\u00E9k\u016F. V\u00E1\u017En\u011B ne\u017E\u00E1douc\u00ED \u00FA\u010Dinky se objevuj\u00ED zejm\u00E9na po n\u00E1hl\u00E9m vysazen\u00ED t\u011Bchto l\u00E9k\u016F a proto se doporu\u010Duje vysazov\u00E1n\u00ED postupn\u00E9. Vysazov\u00E1n\u00ED benzodiazepin\u016F b\u00FDv\u00E1 snaz\u0161\u00ED p\u0159i pou\u017Eit\u00ED kognitivn\u011B behavior\u00E1ln\u00EDch program\u016F." . . "VYSAZOV\u00C1N\u00CD BENZODIAZEPIN\u016E U PACIENT\u016E S \u00DAZKOSTN\u00DDMI PORUCHAMI"@cs . "VYSAZOV\u00C1N\u00CD BENZODIAZEPIN\u016E U PACIENT\u016E S \u00DAZKOSTN\u00DDMI PORUCHAMI" . "Navzdory zv\u00FD\u0161en\u00E9 pozornosti k pod\u00E1v\u00E1n\u00ED antidepresiv a dal\u0161\u00EDch l\u00E9k\u016F k l\u00E9\u010Db\u011B \u00FAzkosti, benzodiazepiny z\u016Fst\u00E1vaj\u00ED nej\u010Dast\u011Bji p\u0159edepisovanou anxiolytickou medikaci pro jejich v\u00FDrazn\u00FD efekt, rychl\u00FD po\u010D\u00E1tek \u00FA\u010Dinku a v\u0161eobecn\u011B dobr\u00E9mu profilu ne\u017E\u00E1douc\u00EDch \u00FA\u010Dink\u016F. Jejich vysazen\u00ED po redukci \u00FAzkosti je prosp\u011B\u0161n\u00E9 proto\u017Ee dlouhodob\u00E9 u\u017E\u00EDv\u00E1n\u00ED souvis\u00ED s \u0159adou ne\u017E\u00E1douc\u00EDch jev\u016F. B\u011Bhem vysazov\u00E1n\u00ED se mohou objevit nov\u00E9 p\u0159\u00EDznaky \u00FAzkosti a to mnoh\u00FDm pacient\u016Fm br\u00E1n\u00ED ve vysazen\u00ED l\u00E9k\u016F. V\u00E1\u017En\u011B ne\u017E\u00E1douc\u00ED \u00FA\u010Dinky se objevuj\u00ED zejm\u00E9na po n\u00E1hl\u00E9m vysazen\u00ED t\u011Bchto l\u00E9k\u016F a proto se doporu\u010Duje vysazov\u00E1n\u00ED postupn\u00E9. Vysazov\u00E1n\u00ED benzodiazepin\u016F b\u00FDv\u00E1 snaz\u0161\u00ED p\u0159i pou\u017Eit\u00ED kognitivn\u011B behavior\u00E1ln\u00EDch program\u016F."@cs . . . "Discontinuation of benzodiazepines in patients with anxiety disorders"@en . "1" . "5"^^ . "P(NS10301)" . . "16" . "Kamar\u00E1dov\u00E1, Dana" . . . "Grambal, Ale\u0161" . "RIV/00098892:_____/13:#0000276" . . . . . "VYSAZOV\u00C1N\u00CD BENZODIAZEPIN\u016E U PACIENT\u016E S \u00DAZKOSTN\u00DDMI PORUCHAMI"@cs . "2"^^ . "Psychiatrie : \u010Dasopis pro modern\u00ED psychiatrii" . "5"^^ . "Despite increasing focus on the use of antidepressants and other drugs for the treatment of anxiety, benzodiazepines have remained a mainstay of anxiolytic pharmacotherapy due to their robust efficacy, rapid onset of therapeutic effect, and generally favorable side effect profile. The discontinuation after anxiety reduction is usually beneficial due to the importance of adverse effects induced by long-term use of benzodiazepines. During treatment discontinuation, new symptoms may emerge and anxiety may return, preventing many patients from successfully discontinuing their treatment. Serious adverse effects are likely to occur only after abrupt discontinuation of benzodiazepine drugs, and they should almost always be tapered. The rate of successful discontinuation of benzodiazepine treatment was significantly higher for the patients receiving the cognitive-behavioral program."@en . . "RIV/00098892:_____/13:#0000276!RIV13-MZ0-00098892" . "115638" . "benzodiazepines, anxiety, cognitive behavioral therapy"@en . .