"2" . "4"^^ . . "000299645400003" . . "186501" . "I, P(GD310/05/H533), S, Z(MSM0021620806)" . "Bartovsk\u00E1, Zofia" . . . "1570-162X" . . "[10D040EC414C]" . "Rozsypal, Hanu\u0161" . "RIV/00064211:_____/11:#0000165!RIV14-MZ0-00064211" . . "Holub, Michal" . "The objectives of our study were to analyse the frequency and functional status of HIV-specific CD8+ T cells and the expression of non-specific activation markers on CD8+ T cells in HIV+ patients. We examined 28 HIV+ patients, including 13 patients not receiving therapy complex antiretroviral therapy (cART) using ELISpot assay and flow cytometry with intracellular and MHC tetramer staining. The results suggested that the alterations of HIV-specific immunity are not influenced by the therapy of HIV infection; whereas, the non-specific chronic immune activation is down-regulated by cART." . "7"^^ . . "9" . . . . "Antiretroviral treatment of HIV infection does not influence HIV-specific immunity but has an impact on Non-specific immune activation" . . "NL - Nizozemsko" . . "Antiretroviral treatment of HIV infection does not influence HIV-specific immunity but has an impact on Non-specific immune activation"@en . "Current HIV Research" . "The objectives of our study were to analyse the frequency and functional status of HIV-specific CD8+ T cells and the expression of non-specific activation markers on CD8+ T cells in HIV+ patients. We examined 28 HIV+ patients, including 13 patients not receiving therapy complex antiretroviral therapy (cART) using ELISpot assay and flow cytometry with intracellular and MHC tetramer staining. The results suggested that the alterations of HIV-specific immunity are not influenced by the therapy of HIV infection; whereas, the non-specific chronic immune activation is down-regulated by cART."@en . . "Antiretroviral therapy; CD38; HIV infection; HIV-specific CD8+ T cells; HLA-DR; Multifunctional CD8+ T cells"@en . . . "RIV/00064211:_____/11:#0000165" . . . . "Antiretroviral treatment of HIV infection does not influence HIV-specific immunity but has an impact on Non-specific immune activation" . . . "Beran, Ond\u0159ej" . . . "Antiretroviral treatment of HIV infection does not influence HIV-specific immunity but has an impact on Non-specific immune activation"@en . . . "3"^^ . .