"Z\u00EDskan\u00E1 neuromyotonie s nevelk\u00FDmi centr\u00E1ln\u00EDmi p\u0159\u00EDznaky s pr\u016Fkazem protil\u00E1tek proti nap\u011B\u0165ov\u011B \u0159\u00EDzen\u00FDm kaliov\u00FDm kan\u00E1l\u016Fm - kazuistika" . "353036" . "V" . . "4" . . . . . "1210-7859" . . "\u010Cesk\u00E1 a slovensk\u00E1 neurologie a neurochirurgie" . . "Acquired Neuromyotonia with Minor Central Symptoms and Antibodies against Voltage-Gated Potassium Channels - a Case Report"@en . "72" . "Latta, J." . . "neuromyotonia; Morvan's disease; voltage-gated potassium channels; arrhythmia; myokymia; fasciculation; central-nervous-system; morvans-syndrome; discharges; emg"@en . "1"^^ . "Z\u00EDskan\u00E1 neuromyotonie s nevelk\u00FDmi centr\u00E1ln\u00EDmi p\u0159\u00EDznaky s pr\u016Fkazem protil\u00E1tek proti nap\u011B\u0165ov\u011B \u0159\u00EDzen\u00FDm kaliov\u00FDm kan\u00E1l\u016Fm - kazuistika" . "Z\u00E1me\u010Dn\u00EDk, Josef" . "[0914A3A703B4]" . "3"^^ . "5"^^ . . . . "CZ - \u010Cesk\u00E1 republika" . "Z\u00EDskan\u00E1 neuromyotonie s nevelk\u00FDmi centr\u00E1ln\u00EDmi p\u0159\u00EDznaky s pr\u016Fkazem protil\u00E1tek proti nap\u011B\u0165ov\u011B \u0159\u00EDzen\u00FDm kaliov\u00FDm kan\u00E1l\u016Fm - kazuistika"@cs . . "A 52-year-old still healthy man developed, over several weeks, a myalgic syndrome with fatigue and muscle weakness, tingling and fasciculation, predominantly in the lower limbs. Such disorders caused inability to walk independently. Upon admission, the clinical findings included muscle weakness and muscle stiffness with tenderness, autonomic symptoms with sweating, intermittent tachycardia, constipation, and also personality and behavioral changes with insomnia and late-night confusion. The electromyography showed a persisting activity with discharges, which were provoked by voluntary activity, and in particular by the stimulation of motor fibres. The patient was treated with carbamazepine and methylprednisolone. Hypertonia, myalgia and central symptoms subsided. At that stage, the results came back with highly elevated antibodies against voltage-gated potassium channels in serum. However, the patient suddenly died of malignant arrhythmia."@en . . . "000269188200013" . . . "RIV/00064203:_____/09:5293" . "Z\u00EDskan\u00E1 neuromyotonie s nevelk\u00FDmi centr\u00E1ln\u00EDmi p\u0159\u00EDznaky s pr\u016Fkazem protil\u00E1tek proti nap\u011B\u0165ov\u011B \u0159\u00EDzen\u00FDm kaliov\u00FDm kan\u00E1l\u016Fm - kazuistika"@cs . . "RIV/00064203:_____/09:5293!RIV10-MZ0-00064203" . . "U 52let\u00E9ho, dosud zdrav\u00E9ho mu\u017Ee se v pr\u016Fb\u011Bhu n\u011Bkolika t\u00FDdn\u016F rozvinul myalgick\u00FD syndrom s \u00FAnavnost\u00ED, slabost\u00ED, brn\u011Bn\u00EDm a z\u00E1\u0161kuby ve svalech, a to zejm\u00E9na na doln\u00EDch kon\u010Detin\u00E1ch (DK). Pro tyto pot\u00ED\u017Ee pak u\u017E nebyl schopen samostatn\u00E9 ch\u016Fze. V klinick\u00E9m n\u00E1lezu p\u0159i p\u0159ijet\u00ED byla slabost a tuhost sval\u016F s bolestivou palpac\u00ED, vegetativn\u00ED p\u0159\u00EDznaky s pocen\u00EDm, intermitentn\u00ED tachykardi\u00ED, z\u00E1cpou, d\u00E1le osobnostn\u00ED a behavior\u00E1ln\u00ED zm\u011Bny s nespavost\u00ED a no\u010Dn\u00ED zmatenost\u00ED. V elektromyografii (EMG) byla patrna klidov\u00E1 trval\u00E1 aktivita s v\u00FDboji, kter\u00E9 byly provokov\u00E1ny voln\u00ED aktivitou a zejm\u00E9na stimulac\u00ED motorick\u00FDch vl\u00E1ken. Nemocn\u00E9ho jsme l\u00E9\u010Dili karbamazepinem a metylprednizolonem. Do\u0161lo k \u00FAstupu hypertonie, bolest\u00ED sval\u016F i centr\u00E1ln\u00EDch p\u0159\u00EDznak\u016F. V t\u00E9 f\u00E1zi do\u0161el siln\u011B pozitivn\u00ED n\u00E1lez autoprotil\u00E1tek proti kaliov\u00FDm kan\u00E1l\u016Fm. Pacient v\u0161ak n\u00E1hle zem\u0159el na malign\u00ED arytmii."@cs . "Ehler, E." . . "Acquired Neuromyotonia with Minor Central Symptoms and Antibodies against Voltage-Gated Potassium Channels - a Case Report"@en . . . "U 52let\u00E9ho, dosud zdrav\u00E9ho mu\u017Ee se v pr\u016Fb\u011Bhu n\u011Bkolika t\u00FDdn\u016F rozvinul myalgick\u00FD syndrom s \u00FAnavnost\u00ED, slabost\u00ED, brn\u011Bn\u00EDm a z\u00E1\u0161kuby ve svalech, a to zejm\u00E9na na doln\u00EDch kon\u010Detin\u00E1ch (DK). Pro tyto pot\u00ED\u017Ee pak u\u017E nebyl schopen samostatn\u00E9 ch\u016Fze. V klinick\u00E9m n\u00E1lezu p\u0159i p\u0159ijet\u00ED byla slabost a tuhost sval\u016F s bolestivou palpac\u00ED, vegetativn\u00ED p\u0159\u00EDznaky s pocen\u00EDm, intermitentn\u00ED tachykardi\u00ED, z\u00E1cpou, d\u00E1le osobnostn\u00ED a behavior\u00E1ln\u00ED zm\u011Bny s nespavost\u00ED a no\u010Dn\u00ED zmatenost\u00ED. V elektromyografii (EMG) byla patrna klidov\u00E1 trval\u00E1 aktivita s v\u00FDboji, kter\u00E9 byly provokov\u00E1ny voln\u00ED aktivitou a zejm\u00E9na stimulac\u00ED motorick\u00FDch vl\u00E1ken. Nemocn\u00E9ho jsme l\u00E9\u010Dili karbamazepinem a metylprednizolonem. Do\u0161lo k \u00FAstupu hypertonie, bolest\u00ED sval\u016F i centr\u00E1ln\u00EDch p\u0159\u00EDznak\u016F. V t\u00E9 f\u00E1zi do\u0161el siln\u011B pozitivn\u00ED n\u00E1lez autoprotil\u00E1tek proti kaliov\u00FDm kan\u00E1l\u016Fm. Pacient v\u0161ak n\u00E1hle zem\u0159el na malign\u00ED arytmii." .