. . "B\u00FCchler, Tom\u00E1\u0161" . . "4" . "Currently there are no standard therapeutical options for patients with metastatic HER2-positive breast cancer after progression on trastuzumab and lapatinib. Retrospective studies have indicated promising activity of trastuzumab retreatment in this clinical situation. Trastuzumab may therefore represent a valid treatment option for these patients in good overall condition."@en . "1"^^ . "Retreatment trastuzumabem po progresi na l\u00E9\u010Db\u011B trastuzumabem a lapatinibem u pacientek s metastatick\u00FDm HER2-pozitivn\u00EDm karcinomem prsu" . . . . "V sou\u010Dasnosti neexistuje standardn\u00ED l\u00E9\u010Dba c\u00EDlen\u00E1 na inhibici HER2 pro pacientky s metastatick\u00FDm HER2-pozitivn\u00EDm karcinomem prsu po progresi na l\u00E9\u010Db\u011B trastuzumabem a lapatinibem. V retrospektivn\u00EDch studi\u00EDch se prok\u00E1zalo, \u017Ee trastuzumab si m\u016F\u017Ee v t\u00E9to situaci zachov\u00E1vat terapeutickou aktivitu a b\u00FDt validn\u00ED l\u00E9\u010Debnou mo\u017Enost\u00ED pro pacientky v dobr\u00E9m celkov\u00E9m stavu."@cs . "Retreatment trastuzumabem po progresi na l\u00E9\u010Db\u011B trastuzumabem a lapatinibem u pacientek s metastatick\u00FDm HER2-pozitivn\u00EDm karcinomem prsu"@cs . . . "1802-4475" . "RIV/00064190:_____/12:#0000366" . "Retreatment with trastuzumab-based therapy after disease progression following lapatinib in HER2-positive metastatic breast cancer"@en . . "V" . "165363" . "Retreatment trastuzumabem po progresi na l\u00E9\u010Db\u011B trastuzumabem a lapatinibem u pacientek s metastatick\u00FDm HER2-pozitivn\u00EDm karcinomem prsu" . "http://www.onkologiecs.cz/pdfs/xon/2012/04/09.pdf" . . . "Retreatment with trastuzumab-based therapy after disease progression following lapatinib in HER2-positive metastatic breast cancer"@en . . "Onkologie" . "CZ - \u010Cesk\u00E1 republika" . "V sou\u010Dasnosti neexistuje standardn\u00ED l\u00E9\u010Dba c\u00EDlen\u00E1 na inhibici HER2 pro pacientky s metastatick\u00FDm HER2-pozitivn\u00EDm karcinomem prsu po progresi na l\u00E9\u010Db\u011B trastuzumabem a lapatinibem. V retrospektivn\u00EDch studi\u00EDch se prok\u00E1zalo, \u017Ee trastuzumab si m\u016F\u017Ee v t\u00E9to situaci zachov\u00E1vat terapeutickou aktivitu a b\u00FDt validn\u00ED l\u00E9\u010Debnou mo\u017Enost\u00ED pro pacientky v dobr\u00E9m celkov\u00E9m stavu." . "Retreatment trastuzumabem po progresi na l\u00E9\u010Db\u011B trastuzumabem a lapatinibem u pacientek s metastatick\u00FDm HER2-pozitivn\u00EDm karcinomem prsu"@cs . "2"^^ . "trastuzumab; lapatinib; breast cancer"@en . . . "[771D985F55CD]" . "1"^^ . "RIV/00064190:_____/12:#0000366!RIV13-MZ0-00064190" . "6" . .