"RIV/00064173:_____/12:#0000384!RIV14-MZ0-00064173" . . . . . "164441" . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . "6" . . "Leukemia Research" . . . . . . "Recurrent chromosomal breakpoints in patients with myelodysplastic syndromes and complex karyotype versus fragile sites" . . . . "We confirmed co-localization of four breakpoints: 5q15, 5q33, 7q21.11 7q32.3 and FS in MDS patients. Their roles in clonal transformation are not yet fully characterized. However, tumor-suppressor genes and/or oncogenes are predicted to reside in these loci. Further microarray analyses of the affected chromosomal regions in combination with molecular-cytogenetic approaches will help to elucidate the degree of correlation with fragile sites." . . "14"^^ . "3"^^ . . "1"^^ . . . . "0145-2126" . "chromosomal breakpoints; myelodysplastic syndrome"@en . "Recurrent chromosomal breakpoints in patients with myelodysplastic syndromes and complex karyotype versus fragile sites"@en . "Recurrent chromosomal breakpoints in patients with myelodysplastic syndromes and complex karyotype versus fragile sites"@en . "Recurrent chromosomal breakpoints in patients with myelodysplastic syndromes and complex karyotype versus fragile sites" . "P(LC535), P(OC10043), V, Z(MSM0021620808), Z(MZ0UHKT2005), Z(MZ0VFN2005)" . . . . "000302961400003" . "We confirmed co-localization of four breakpoints: 5q15, 5q33, 7q21.11 7q32.3 and FS in MDS patients. Their roles in clonal transformation are not yet fully characterized. However, tumor-suppressor genes and/or oncogenes are predicted to reside in these loci. Further microarray analyses of the affected chromosomal regions in combination with molecular-cytogenetic approaches will help to elucidate the degree of correlation with fragile sites."@en . "[CA52CF16E1B8]" . "36" . "\u010Cern\u00E1, Olga" . "RIV/00064173:_____/12:#0000384" . "10.1016/j.leukres.2012.02.006" .