"Riociguat for the treatment of chronic thromboembolic pulmonary hypertension" . "Wilkins, Martin R." . "Mayer, Eckhard" . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . "Riociguat, a memberof a new class of compounds (soluble guanylate cyclase stimulators), has been shown in previous clinical studies to be beneficial in the treatment of chronic thromboembolic pulmonary hypertension.In this phase 3, multicentre, randomized, double-blind, placebo-controlled study, we randomly assigned 261 patients with inoperable chronic thromboembolic pulmonary hypertension or persistent or recurrent pulmonary hypertension after pulmonary endarterectomy to receive placebo or riociguat."@en . "Simonneau, Gerald" . "Jansa, Pavel" . "D'Armini, Andrea M." . "13"^^ . "0028-4793" . . . . . "Ghofrani, Hossein-Ardeschir" . "Riociguat for the treatment of chronic thromboembolic pulmonary hypertension"@en . "Hoeper, Marius M." . . "http://www.nejm.org/doi/full/10.1056/NEJMoa1209657" . . "11"^^ . "Neuser, Dieter" . . "Wang, Chen" . . "Kim, Nick H." . "RIV/00064165:_____/13:10195003" . "Grimminger, Friedrich" . "Riociguat, a memberof a new class of compounds (soluble guanylate cyclase stimulators), has been shown in previous clinical studies to be beneficial in the treatment of chronic thromboembolic pulmonary hypertension.In this phase 3, multicentre, randomized, double-blind, placebo-controlled study, we randomly assigned 261 patients with inoperable chronic thromboembolic pulmonary hypertension or persistent or recurrent pulmonary hypertension after pulmonary endarterectomy to receive placebo or riociguat." . "N" . "New England Journal of Medicine" . . . "102972" . . "[DCBD029CBE81]" . "Fritsch, Arno" . . . "1"^^ . "Riociguat for the treatment of chronic thromboembolic pulmonary hypertension" . "endarterectomy; riociguat; chronic thromboembolic pulmonary hypertension"@en . . "RIV/00064165:_____/13:10195003!RIV14-MZ0-00064165" . . "Weimann, Gerrit" . "Riociguat for the treatment of chronic thromboembolic pulmonary hypertension"@en . "369" . "4" . "000322223900007" . "10.1056/NEJMoa1209657" .