"The risk of development of type 2 diabetes (DM2) is signif icantly increased in the patients suffering from psychotic diseases such as schizophrenia, depressive disorder or bipolar affective disorder. There are more of the causes of this phenomenon. The patients with abovementioned diseases are characterized by unhealthy lifestyle and also sufferfrom an increased occurence of the components of the metabolic syndrome (MetS). Treatment with some atypical antipsychotics (AAP) increases the risk of development of DM2. Atypical antipsychotics can be divided into several groups according to their influencing on the receptors of the neurotransmitters. Spectrum of the receptors, influenced by the individual AAP, determines their effects on the weight gain, plasma lipid levels and the risk of DM2 development."@en . "124063" . . . "Atypick\u00E1 antipsychotika a diabetes mellitus"@cs . "RIV/00064165:_____/12:12278" . "Atypick\u00E1 antipsychotika a diabetes mellitus"@cs . "Psychiatrie pro praxi" . "Atypical antipsychotics and diabetes mellitus"@en . "[05145B02240E]" . "I" . . "4"^^ . "Atypical antipsychotics and diabetes mellitus"@en . . "Zeman, Miroslav" . . . . . . . . "2"^^ . "RIV/00064165:_____/12:12278!RIV13-MZ0-00064165" . "U nemocn\u00FDch s psychotick\u00FDmi onemocn\u011Bn\u00EDmi, jako je schizofrenie, deprese \u010Di bipol\u00E1rn\u00ED afektivn\u00ED porucha, je v\u00FDznamn\u011B zv\u00FD\u0161eno riziko manifestace diabetes mellitus 2. typu (DM2). P\u0159\u00ED\u010Din tohoto stavu je v\u00EDce. Nemocn\u00ED uveden\u00FDmi chorobami \u010Dasto \u017Eij\u00ED nezdrav\u00FDm \u017Eivotn\u00EDm stylem a trp\u00ED zv\u00FD\u0161en\u00FDm v\u00FDskytem komponent metabolick\u00E9ho syndromu (MetS). L\u00E9\u010Dba n\u011Bkter\u00FDmi atypick\u00FDmi antipsychotiky (AAP) zvy\u0161uje riziko DM2. Atypick\u00E1 antipsychotika lze d\u011Blit do n\u011Bkolika skupin podle p\u016Fsoben\u00ED na r\u016Fzn\u00E9 receptory neurop\u0159ena\u0161e\u010D\u016F. Spektrum receptor\u016F, na kter\u00E9 jednotliv\u00E1 AAP p\u016Fsob\u00ED, ovliv\u0148uje jejich \u00FA\u010Dinky na hmotnost, hladiny lipid\u016F a riziko vzniku DM2." . "4" . . "2"^^ . . "U nemocn\u00FDch s psychotick\u00FDmi onemocn\u011Bn\u00EDmi, jako je schizofrenie, deprese \u010Di bipol\u00E1rn\u00ED afektivn\u00ED porucha, je v\u00FDznamn\u011B zv\u00FD\u0161eno riziko manifestace diabetes mellitus 2. typu (DM2). P\u0159\u00ED\u010Din tohoto stavu je v\u00EDce. Nemocn\u00ED uveden\u00FDmi chorobami \u010Dasto \u017Eij\u00ED nezdrav\u00FDm \u017Eivotn\u00EDm stylem a trp\u00ED zv\u00FD\u0161en\u00FDm v\u00FDskytem komponent metabolick\u00E9ho syndromu (MetS). L\u00E9\u010Dba n\u011Bkter\u00FDmi atypick\u00FDmi antipsychotiky (AAP) zvy\u0161uje riziko DM2. Atypick\u00E1 antipsychotika lze d\u011Blit do n\u011Bkolika skupin podle p\u016Fsoben\u00ED na r\u016Fzn\u00E9 receptory neurop\u0159ena\u0161e\u010D\u016F. Spektrum receptor\u016F, na kter\u00E9 jednotliv\u00E1 AAP p\u016Fsob\u00ED, ovliv\u0148uje jejich \u00FA\u010Dinky na hmotnost, hladiny lipid\u016F a riziko vzniku DM2."@cs . . "Psychotic disorders; atypical antipsychotics; weight gain; dyslipidemia; type 2 diabetes mellitus"@en . "Jir\u00E1k, Roman" . . "http://www.psychiatriepropraxi.cz/pdfs/psy/2012/04/05.pdf" . "1213-0508" . "13" . . "Atypick\u00E1 antipsychotika a diabetes mellitus" . "Atypick\u00E1 antipsychotika a diabetes mellitus" . "CZ - \u010Cesk\u00E1 republika" . . .